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PRNP 抗体

PRNP 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2854915
发货至: 中国
  • 抗原 See all PRNP 抗体
    PRNP (Prion Protein (PRNP))
    适用
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    宿主
    • 86
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    克隆类型
    • 77
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    多克隆
    标记
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    This PRNP antibody is un-conjugated
    应用范围
    • 54
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    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    交叉反应
    人, 小鼠
    产品特性
    Rabbit Polyclonal antibody to PRP (prion protein)
    PRP antibody
    纯化方法
    Purified by antigen-affinity chromatography.
    免疫原
    Recombinant protein encompassing a sequence within the center region of human Prion Protein (PrP). The exact sequence is proprietary.
    亚型
    IgG
    Top Product
    Discover our top product PRNP Primary Antibody
  • 应用备注
    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    说明

    Positive Control: Neuro2A , NIH-3T3 , C2C12 , IMR32

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.36 mg/mL
    缓冲液
    1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.01 % Thimerosal
    储存液
    Thimerosal (Merthiolate)
    注意事项
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原
    PRNP (Prion Protein (PRNP))
    别名
    prion protein (PRNP 产品)
    背景
    The protein encoded by this gene is a membrane glycosylphosphatidylinositol-anchored glycoprotein that tends to aggregate into rod-like structures. The encoded protein contains a highly unstable region of five tandem octapeptide repeats. This gene is found on chromosome 20, approximately 20 kbp upstream of a gene which encodes a biochemically and structurally similar protein to the one encoded by this gene. Mutations in the repeat region as well as elsewhere in this gene have been associated with Creutzfeldt-Jakob disease, fatal familial insomnia, Gerstmann-Straussler disease, Huntington disease-like 1, and kuru. Alternative splicing results in multiple transcript variants encoding the same protein.

    Cellular Localization: Cell membrane, Lipid-anchor , GPI-anchor , Golgi apparatus
    分子量
    28 kDa
    基因ID
    5621
    UniProt
    P04156, F7VJQ1
    途径
    Transition Metal Ion Homeostasis, Activated T Cell Proliferation
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