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PRNP 抗体

PRNP 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2854915
发货至: 中国
  • 抗原 See all PRNP 抗体
    PRNP (Prion Protein (PRNP))
    适用
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    宿主
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    克隆类型
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    多克隆
    标记
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    This PRNP antibody is un-conjugated
    应用范围
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    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    交叉反应
    人, 小鼠
    产品特性
    Rabbit Polyclonal antibody to PRP (prion protein)
    PRP antibody
    纯化方法
    Purified by antigen-affinity chromatography.
    免疫原
    Recombinant protein encompassing a sequence within the center region of human Prion Protein (PrP). The exact sequence is proprietary.
    亚型
    IgG
    Top Product
    Discover our top product PRNP Primary Antibody
  • 应用备注
    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    说明

    Positive Control: Neuro2A , NIH-3T3 , C2C12 , IMR32

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.36 mg/mL
    缓冲液
    1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.01 % Thimerosal
    储存液
    Thimerosal (Merthiolate)
    注意事项
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原
    PRNP (Prion Protein (PRNP))
    别名
    prion protein (PRNP 产品)
    别名
    ASCR antibody, AltPrP antibody, CD230 antibody, CJD antibody, GSS antibody, KURU antibody, PRIP antibody, PrP antibody, PrP27-30 antibody, PrP33-35C antibody, PrPc antibody, p27-30 antibody, Prn antibody, Prn-p antibody, prp antibody, cjd antibody, prion antibody, prp(c) antibody, MGC84114 antibody, PRP antibody, PRPC antibody, Prp antibody, SIP antibody, PRNP antibody, AA960666 antibody, AI325101 antibody, PrP antibody, PrPC antibody, PrPSc antibody, Prn-i antibody, Sinc antibody, prP27-30 antibody, prP33-35C antibody, PrP-1 antibody, PrP1 antibody, prnprs1 antibody, stPrP-1 antibody, zgc:123004 antibody, prion protein antibody, prion protein S homeolog antibody, prion protein b antibody, PRNP antibody, Prnp antibody, prnp.S antibody, prnpb antibody
    背景
    The protein encoded by this gene is a membrane glycosylphosphatidylinositol-anchored glycoprotein that tends to aggregate into rod-like structures. The encoded protein contains a highly unstable region of five tandem octapeptide repeats. This gene is found on chromosome 20, approximately 20 kbp upstream of a gene which encodes a biochemically and structurally similar protein to the one encoded by this gene. Mutations in the repeat region as well as elsewhere in this gene have been associated with Creutzfeldt-Jakob disease, fatal familial insomnia, Gerstmann-Straussler disease, Huntington disease-like 1, and kuru. Alternative splicing results in multiple transcript variants encoding the same protein.

    Cellular Localization: Cell membrane, Lipid-anchor , GPI-anchor , Golgi apparatus
    分子量
    28 kDa
    基因ID
    5621
    UniProt
    P04156, F7VJQ1
    途径
    Transition Metal Ion Homeostasis, Activated T Cell Proliferation
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