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Angiopoietin 2 抗体

ANGPT2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2854896
发货至: 中国
  • 抗原 See all Angiopoietin 2 (ANGPT2) 抗体
    Angiopoietin 2 (ANGPT2)
    适用
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    宿主
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    克隆类型
    • 67
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    多克隆
    标记
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    This Angiopoietin 2 antibody is un-conjugated
    应用范围
    • 61
    • 31
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    • 13
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    • 10
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    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    交叉反应
    人, 小鼠
    产品特性
    Rabbit Polyclonal antibody to Angiopoietin 2 (angiopoietin-2)
    Angiopoietin 2 antibody
    纯化方法
    Purified by antigen-affinity chromatography.
    免疫原
    Recombinant protein encompassing a sequence within the center region of human Angiopoietin 2. The exact sequence is proprietary.
    亚型
    IgG
    Top Product
    Discover our top product ANGPT2 Primary Antibody
  • 应用备注
    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    说明

    Validation: Orthogonal

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1.04 mg/mL
    缓冲液
    1XPBS pH 7, 20 % Glycerol, 0.025 % ProClin 300
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Gu, Zhang, Han, Gao, Cui, Sun, Niu, You, Huang, Chang, Wang, Yeh: "Targeting the ERβ/Angiopoietin-2/Tie-2 signaling-mediated angiogenesis with the FDA-approved anti-estrogen Faslodex to increase the Sunitinib sensitivity in RCC." in: Cell death & disease, Vol. 11, Issue 5, pp. 367, (2020) (PubMed).

    Fischer, Seifen, Baer, Jung, Mertens, Scheller, Zacharowski, Hofmann, Maier, Urbschat: "The Fibrin Cleavage Product Bβ15-42 Channels Endothelial and Tubular Regeneration in the Post-acute Course During Murine Renal Ischemia Reperfusion Injury." in: Frontiers in pharmacology, Vol. 9, pp. 369, (2018) (PubMed).

  • 抗原
    Angiopoietin 2 (ANGPT2)
    别名
    angiopoietin 2 (ANGPT2 产品)
    别名
    AGPT2 antibody, ANG2 antibody, Agpt2 antibody, Ang-2 antibody, Ang2 antibody, ang2 antibody, angpt2 antibody, ANGIOPOIETIN-2 antibody, ANG-2 antibody, ANGPT2 antibody, Angrp antibody, Rnase5b antibody, ANG3 antibody, C11orf2 antibody, C11orf3 antibody, FFR antibody, angiopoietin 2 antibody, angiopoietin 2b antibody, angiogenin, ribonuclease A family, member 2 antibody, VPS51, GARP complex subunit antibody, ANGPT2 antibody, Angpt2 antibody, angpt2b antibody, Ang2 antibody, VPS51 antibody
    背景
    The protein encoded by this gene is an antagonist of angiopoietin 1 (ANGPT1) and endothelial TEK tyrosine kinase (TIE-2, TEK). The encoded protein disrupts the vascular remodeling ability of ANGPT1 and may induce endothelial cell apoptosis. Three transcript variants encoding three different isoforms have been found for this gene.

    Cellular Localization: Secreted
    分子量
    57 kDa
    基因ID
    285
    UniProt
    O15123
    途径
    RTK signaling
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