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RAC1 抗体 (Center)

Name: RAC1 抗体 (Center)
Brand: antibodies-online
SKU: ABIN2854858
Availability: OutOfStock

适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated

WB Image Sample (30 ug of whole cell lysate) A: Hela B: Raji 12% SDS PAGE antibody diluted at 1:1000 (RAC1 抗体 (Center))

IHC-P Image Immunohistochemical analysis of paraffin-embedded H441 xenograft , using RAC1, antibody at 1:100 dilution. (RAC1 抗体 (Center))

IHC

WB Image Sample (50 ug of whole cell lysate) A: mouse liver 12% SDS PAGE antibody diluted at 1:1000 (RAC1 抗体 (Center))

STAT3 signaling is downstream of Rac activity during invasion of human breast cancer(A) Immunohistochemistry shows that Rac1 protein expression (left panel) and STAT3 phosphorylation on Ser727 (right panel) frequently coincide in human breast cancer. (RAC1 抗体 (Center))

IHC

C/EBPδ represses RhoA expression and contributes to attenuated migration of IL-1β-treated astrocytes. (RAC1 抗体 (Center))

5 images

(2 references)

产品编号 ABIN2854858

发货至: 中国

Datasheet as PDF

抗原 See all RAC1 抗体

RAC1
抗原表位
18

15

10

5

4

3

2

2

2

1

1

1

1

1

1

1
Center
适用
82

51

37

4

4

4

4

4

4

4

3

3

3

2

1

1

1
人, 小鼠
宿主
74

7

1
兔
Compatible Secondaries
克隆类型
74

8
多克隆
标记
35

5

5

5

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1
This RAC1 antibody is un-conjugated
应用范围
56

26

26

22

15

10

8

4

3

2

1

1

1

1

1

1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

交叉反应

小鸡, 犬, 猪, 大鼠, 非洲爪蟾, 牛, Xenopus tropicalis

交叉反应（详细）

Chicken (90 %), Dog (90 %), Pig (90 %), Rat (90 %), Xenopus laevis (90 %), Bovine (90 %), Xenopus tropicalis (90 %)

产品特性

Rabbit Polyclonal antibody to RAC1 (ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1))
RAC1 antibody

纯化方法

Purified by antigen-affinity chromatography.

免疫原

Recombinant protein encompassing a sequence within the center region of human RAC1. The exact sequence is proprietary.

亚型

IgG
anti-RAC1 (AA 1-192) antibody
适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-RAC1 antibody
适用: 人, 大鼠 WB, ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 1301CT276-121-104 unconjugated

anti-RAC1 (AA 11-185) antibody
适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-RAC1 antibody
适用: 人, 大鼠 WB, IHC (p), FACS 宿主: 小鼠 Monoclonal 1301CT276-121-104 unconjugated

anti-RAC1 (pSer71) antibody
适用: 人, 小鼠, 大鼠 WB, IF (cc), IF (p), IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-RAC1 (AA 101-192) antibody
适用: 人, 小鼠 ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-RAC1 antibody
适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 小鼠 Monoclonal 13C4 unconjugated

anti-RAC1 (AA 100-192) antibody (Biotin)
适用: 人 WB, IHC 宿主: 兔 Polyclonal Biotin

anti-RAC1 (AA 100-192) antibody (PE)
适用: 人 WB, IHC 宿主: 兔 Polyclonal PE

anti-RAC1 (AA 100-192) antibody (PerCP)
适用: 人 WB, IHC 宿主: 兔 Polyclonal PerCP

应用备注

Suggested dilution Reference IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceIHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:3000*

说明

Positive Control: 293T , A431 , HeLa , HepG2 , Molt-4 , Raji , mouse liver

限制

仅限研究用
状态

Liquid

浓度

1 mg/mL

缓冲液

0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

储存液

Thimerosal (Merthiolate)

注意事项

This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

-20 °C

储存方法

Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
Wang, Hsu, Ko, Chiu, Kan, Lai, Wang: "Astrocytic CCAAT/Enhancer-Binding Protein Delta Contributes to Glial Scar Formation and Impairs Functional Recovery After Spinal Cord Injury." in: Molecular neurobiology, Vol. 53, Issue 9, pp. 5912-5927, (2018) (PubMed).

Katz, Sims, Sproul, Caldwell, Dixon, Meehan, Harrison: "Targeting of Rac GTPases blocks the spread of intact human breast cancer." in: Oncotarget, Vol. 3, Issue 6, pp. 608-19, (2012) (PubMed).
抗原

RAC1

Abstract

RAC1 产品

别名

Rac-1 antibody, TC-25 antibody, p21-Rac1 antibody, AL023026 antibody, D5Ertd559e antibody, RAC2 antibody, CRAC1A antibody, rac1 antibody, wu:fd16e02 antibody, zgc:55823 antibody, zgc:55917 antibody, zgc:86934 antibody, 2248 antibody, CG2248 antibody, D-Rac antibody, D-Rac 1 antibody, D-Rac1 antibody, DRac antibody, DRac1 antibody, DRacA antibody, Dm Rac1 antibody, DmRAC antibody, DmRAC1 antibody, Dmel\CG2248 antibody, Dmrac1 antibody, Drac antibody, Drac1 antibody, Drac1a antibody, DracA antibody, GTPase Rac1 antibody, P40792 antibody, RAC1 antibody, Rac antibody, Rac GTPase antibody, Rac3 antibody, RacA antibody, dRac antibody, dRac1 antibody, drac1 antibody, rac antibody, Xrac antibody, mig5 antibody, p21-rac1 antibody, tc-25 antibody, Rac family small GTPase 1 antibody, RAS-related C3 botulinum substrate 1 antibody, ras-related C3 botulinum toxin substrate 1 antibody, ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) antibody, Rac family small GTPase 1a antibody, CG2248 gene product from transcript CG2248-RB antibody, Rac family small GTPase 1 L homeolog antibody, ras homolog family member G antibody, RAC1 antibody, Rac1 antibody, rac1a antibody, rac1.L antibody, RHOG antibody

背景

The protein encoded by this gene is a GTPase which belongs to the RAS superfamily of small GTP-binding proteins. Members of this superfamily appear to regulate a diverse array of cellular events, including the control of cell growth, cytoskeletal reorganization, and the activation of protein kinases. Two transcript variants encoding different isoforms have been found for this gene.

Cellular Localization: Cell membrane, Lipid-anchor, Cytoplasmic side (By similarity) , Melanosome

分子量

21 kDa

基因ID

5879

途径

WNT signaling, Regulation of Actin Filament Polymerization, Cell-Cell Junction Organization, Thromboxane A2 Receptor Signaling, VEGF Signaling