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SOD1 抗体

KO Validated SOD1 适用: 人 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2854793
发货至: 中国
  • 抗原 See all SOD1 抗体
    SOD1 (Superoxide Dismutase 1, Soluble (SOD1))
    适用
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    宿主
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    克隆类型
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    多克隆
    标记
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    This SOD1 antibody is un-conjugated
    应用范围
    • 210
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    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    交叉反应
    Alligator, Avian, 人, 小鼠, 大鼠
    产品特性
    Rabbit Polyclonal antibody to SOD1 (superoxide dismutase 1, soluble)
    SOD1 antibody
    纯化方法
    Purified by antigen-affinity chromatography.
    质量等级
    KO Validated
    免疫原
    Recombinant protein encompassing a sequence within the center region of human SOD1. The exact sequence is proprietary.
    亚型
    IgG
    Top Product
    Discover our top product SOD1 Primary Antibody
  • 应用备注
    WB: 1:500-1:10000. IHC-P: 1:100-1:1000. ELISA: 1:1000-1:10000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    说明

    Positive Control: mouse brain , Rat brain , NT2D1 , 293T

    Validation: KO/KD, Orthogonal

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.15 mg/mL
    缓冲液
    1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.025 % ProClin 300
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Balhorn, Hartmann, Schupp: "Aldosterone Induces DNA Damage and Activation of Nrf2 Mainly in Tubuli of Mouse Kidneys." in: International journal of molecular sciences, Vol. 21, Issue 13, (2020) (PubMed).

    Parry, Kephart, Mumford, Romero, Mobley, Zhang, Roberts, Kavazis: "Ketogenic diet increases mitochondria volume in the liver and skeletal muscle without altering oxidative stress markers in rats." in: Heliyon, Vol. 4, Issue 11, pp. e00975, (2018) (PubMed).

    Gentile, Fornai, Pellegrini, Colucci, Benvenuti, Duranti, Masi, Carpi, Nieri, Nericcio, Garelli, Virdis, Pistelli, Blandizzi, Antonioli: "Luteolin Prevents Cardiometabolic Alterations and Vascular Dysfunction in Mice With HFD-Induced Obesity." in: Frontiers in pharmacology, Vol. 9, pp. 1094, (2018) (PubMed).

    Mowry, Kavazis, Sirman, Potts, Hood: "Reproduction Does Not Adversely Affect Liver Mitochondrial Respiratory Function but Results in Lipid Peroxidation and Increased Antioxidants in House Mice." in: PLoS ONE, Vol. 11, Issue 8, pp. e0160883, (2017) (PubMed).

    Brand, Amann, Mandel, Zimnol, Schupp: "Oxidative DNA damage in kidneys and heart of hypertensive mice is prevented by blocking angiotensin II and aldosterone receptors." in: PLoS ONE, Vol. 9, Issue 12, pp. e115715, (2015) (PubMed).

  • 抗原
    SOD1 (Superoxide Dismutase 1, Soluble (SOD1))
    别名
    superoxide dismutase 1 (SOD1 产品)
    别名
    LOC692639 antibody, ALS antibody, ALS1 antibody, IPOA antibody, SOD antibody, hSod1 antibody, homodimer antibody, CG11793 antibody, Cu antibody, Cu-Zn SOD antibody, Cu/Zn SOD antibody, Cu/Zn sod antibody, Cu/Zn superoxide dismutase antibody, Cu/ZnSOD antibody, CuSOD antibody, CuZn SOD antibody, CuZn-SOD antibody, CuZn-SOD1 antibody, CuZnSOD antibody, Cu[2+]/Zn[2+]SOD antibody, Dmel\\CG11793 antibody, G antibody, Mn SOD antibody, SOD-1 antibody, SOD1 antibody, Sod-1 antibody, Sod1 antibody, To antibody, To-1 antibody, Zn SOD antibody, Zn Sod antibody, Zn-SOD antibody, ZnSod antibody, cSOD antibody, cSod antibody, dSOD1 antibody, l(3)108 antibody, l(3)68Af' antibody, l(3)G antibody, sod antibody, sod1 antibody, CU/ZN-SOD antibody, SODC antibody, DKFZP469M1833 antibody, B430204E11Rik antibody, Cu/Zn-SOD antibody, Ipo-1 antibody, Ipo1 antibody, SOD1L1 antibody, XSODB antibody, als antibody, als1 antibody, ipoa antibody, sod1-a antibody, ZSOD antibody, cuzn antibody, Cu/Zn superoxide dismutase antibody, superoxide dismutase 1 antibody, Superoxide dismutase 1 antibody, superoxide dismutase 1, soluble antibody, superoxide dismutase 1 S homeolog antibody, Superoxide dismutase [Cu-Zn] antibody, superoxide dismutase 1 L homeolog antibody, superoxide dismutase [Cu-Zn]-like antibody, superoxide dismutase [Cu-Zn] antibody, superoxide dismutase Sod1 antibody, SOD antibody, SOD1 antibody, Sod1 antibody, sod1 antibody, sod1.S antibody, sod-1 antibody, sod1.L antibody, LOC101451855 antibody, LOC101115136 antibody
    背景
    The protein encoded by this gene binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. The encoded isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis. Rare transcript variants have been reported for this gene.

    Cellular Localization: Cytoplasm
    分子量
    16 kDa
    基因ID
    6647
    UniProt
    P00441
    途径
    Sensory Perception of Sound, Transition Metal Ion Homeostasis
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