PLAUR 抗体
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- 抗原 See all PLAUR 抗体
- PLAUR (Plasminogen Activator, Urokinase Receptor (PLAUR))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PLAUR antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 交叉反应
- 人
- 产品特性
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Rabbit Polyclonal antibody to uPAR (plasminogen activator, urokinase receptor)
uPAR antibody - 纯化方法
- Purified by antigen-affinity chromatography.
- 质量等级
- KO Validated
- 免疫原
- Recombinant protein encompassing a sequence within the center region of human uPAR. The exact sequence is proprietary.
- 亚型
- IgG
- Top Product
- Discover our top product PLAUR Primary Antibody
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- 应用备注
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- 说明
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Positive Control: U87-MG , HeLa
Validation: Comparison, KO/KD
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.34 mg/mL
- 缓冲液
- 1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.025 % ProClin 300
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- 抗原
- PLAUR (Plasminogen Activator, Urokinase Receptor (PLAUR))
- 别名
- plasminogen activator, urokinase receptor (PLAUR 产品)
- 背景
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This gene encodes the receptor for urokinase plasminogen activator and, given its role in localizing and promoting plasmin formation, likely influences many normal and pathological processes related to cell-surface plasminogen activation and localized degradation of the extracellular matrix. It binds both the proprotein and mature forms of urokinase plasminogen activator and permits the activation of the receptor-bound pro-enzyme by plasmin. The protein lacks transmembrane or cytoplasmic domains and may be anchored to the plasma membrane by a glycosyl-phosphatidylinositol (GPI) moiety following cleavage of the nascent polypeptide near its carboxy-terminus. However, a soluble protein is also produced in some cell types. Alternative splicing results in multiple transcript variants encoding different isoforms. The proprotein experiences several post-translational cleavage reactions that have not yet been fully defined.
Cellular Localization: Isoform 1: Cell membrane, Lipid-anchor , GPI-anchor , Isoform 2: Secreted - 分子量
- 37 kDa
- 基因ID
- 5329
- UniProt
- Q03405
- 途径
- Inositol Metabolic Process
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