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FANCC 抗体 (Center)

FANCC 适用: 人, 小鼠 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2854743
发货至: 中国
  • 抗原 See all FANCC 抗体
    FANCC (Fanconi Anemia, Complementation Group C (FANCC))
    抗原表位
    • 15
    • 11
    • 8
    • 7
    • 7
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Center
    适用
    • 61
    • 5
    • 2
    人, 小鼠
    宿主
    • 58
    • 3
    克隆类型
    • 59
    • 2
    多克隆
    标记
    • 25
    • 5
    • 5
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This FANCC antibody is un-conjugated
    应用范围
    • 47
    • 26
    • 22
    • 19
    • 14
    • 13
    • 13
    • 8
    • 7
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
    产品特性
    Rabbit Polyclonal antibody to FANCC (Fanconi anemia, complementation group C)
    FANCC antibody [N1C1]
    纯化方法
    Purified by antigen-affinity chromatography.
    免疫原
    Recombinant protein encompassing a sequence within the center region of human FANCC. The exact sequence is proprietary.
    亚型
    IgG
    Top Product
    Discover our top product FANCC Primary Antibody
  • 应用备注
    Suggested dilution Reference ICC/IF 1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:3000*
    说明

    Positive Control: 293T , A431 , HeLa , HepG2 , NIH-3T3

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.989 mg/mL
    缓冲液
    0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
    储存液
    Thimerosal (Merthiolate)
    注意事项
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Pan, Wang, Chen, Ding, Jiang, Gao, Mo, Huang, Lou, Cao: "Deleterious Mutations in DNA Repair Gene FANCC Exist in BRCA1/2-Negative Chinese Familial Breast and/or Ovarian Cancer Patients." in: Frontiers in oncology, Vol. 9, pp. 169, (2019) (PubMed).

  • 抗原
    FANCC (Fanconi Anemia, Complementation Group C (FANCC))
    别名
    FANCC (FANCC 产品)
    别名
    zgc:154105 antibody, FANCC antibody, fa3 antibody, fac antibody, facc antibody, FA3 antibody, FAC antibody, FACC antibody, BB116513 antibody, Facc antibody, Fanconi anemia complementation group C antibody, Fanconi anemia, complementation group C antibody, Fanconi anemia complementation group C L homeolog antibody, FANCC antibody, fancc antibody, fancc.L antibody, Fancc antibody
    背景
    The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity, they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group C.

    Cellular Localization: Nucleus , Cytoplasm
    分子量
    63 kDa
    基因ID
    2176
    途径
    DNA Damage Repair
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