POLG 抗体 (C-Term)
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- 抗原 See all POLG 抗体
- POLG (Polymerase (DNA Directed), gamma (POLG))
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抗原表位
- C-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This POLG antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunoprecipitation (IP)
- 交叉反应
- 人, 大鼠
- 产品特性
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Rabbit Polyclonal antibody to DNA polymerase gamma (polymerase (DNA directed), gamma)
DNA polymerase gamma antibody - 纯化方法
- Purified by antigen-affinity chromatography.
- 免疫原
- Recombinant protein encompassing a sequence within the C-terminus region of human DNA polymerase gamma. The exact sequence is proprietary.
- 亚型
- IgG
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anti-Polymerase (DNA Directed), gamma (POLG) (AA 1101-1239) antibody
POLG 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), ICC, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Polymerase (DNA Directed), gamma (POLG) (AA 1041-1239) antibodyPOLG 适用: 人 WB, ELISA, IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Polymerase (DNA Directed), gamma (POLG) antibodyPOLG 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
anti-Polymerase (DNA Directed), gamma (POLG) (AA 1120-1148), (C-Term) antibodyPOLG 适用: 人, 小鼠 WB, IHC (p), IF, FACS 宿主: 兔 Polyclonal unconjugated
anti-Polymerase (DNA Directed), gamma (POLG) (AA 446-590) antibodyPOLG 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Polymerase (DNA Directed), gamma (POLG) (AA 242-291) antibodyPOLG 适用: 人, 小鼠, 大鼠, Cow, Bat, Hamster, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Polymerase (DNA Directed), gamma (POLG) (N-Term) antibodyPOLG 适用: 人, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Polymerase (DNA Directed), gamma (POLG) (N-Term) antibodyPOLG 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, Saccharomyces cerevisiae, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- 说明
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Positive Control: Rat testis , MCF-7 , MDA-MB-231
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.67 mg/mL
- 缓冲液
- 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- 抗原
- POLG (Polymerase (DNA Directed), gamma (POLG))
- 别名
- DNA polymerase gamma (POLG 产品)
- 别名
- POLG antibody, MDP1 antibody, MIRAS antibody, MTDPS4A antibody, MTDPS4B antibody, PEO antibody, POLG1 antibody, POLGA antibody, SANDO antibody, SCAE antibody, AA409516 antibody, PolgA antibody, polymerase (DNA) gamma, catalytic subunit L homeolog antibody, DNA polymerase gamma, catalytic subunit antibody, polymerase (DNA directed), gamma antibody, polg.L antibody, Polg antibody, POLG antibody, polg antibody
- 物质类
- Viral Protein
- 背景
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Mitochondrial DNA polymerase is heterotrimeric, consisting of a homodimer of accessory subunits plus a catalytic subunit. The protein encoded by this gene is the catalytic subunit of mitochondrial DNA polymerase. The encoded protein contains a polyglutamine tract near its N-terminus that may be polymorphic. Defects in this gene are a cause of progressive external ophthalmoplegia with mitochondrial DNA deletions 1 (PEOA1), sensory ataxic neuropathy dysarthria and ophthalmoparesis (SANDO), Alpers-Huttenlocher syndrome (AHS), and mitochondrial neurogastrointestinal encephalopathy syndrome (MNGIE). Two transcript variants encoding the same protein have been found for this gene.
Cellular Localization: Mitochondrion - 分子量
- 140 kDa
- 基因ID
- 5428
- UniProt
- P54098
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