CCR8 抗体 (C-Term)
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- 抗原 See all CCR8 抗体
- CCR8 (Chemokine (C-C Motif) Receptor 8 (CCR8))
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抗原表位
- C-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CCR8 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 交叉反应
- 人
- 产品特性
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Rabbit Polyclonal antibody to CCR8 (chemokine (C-C motif) receptor 8)
CCR8 antibody - 纯化方法
- Purified by antigen-affinity chromatography.
- 免疫原
- Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human CCR8. The exact sequence is proprietary.
- 亚型
- IgG
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- 应用备注
- WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- 说明
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Positive Control: K562
Validation: Orthogonal
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- 1XPBS ( pH 7), 20 % Glycerol, 0.01 % Thimerosal
- 储存液
- Thimerosal (Merthiolate)
- 注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- 抗原
- CCR8 (Chemokine (C-C Motif) Receptor 8 (CCR8))
- 别名
- C-C motif chemokine receptor 8 (CCR8 产品)
- 别名
- CC-CKR-8 antibody, CCR-8 antibody, CDw198 antibody, CKRL1 antibody, CMKBR8 antibody, CMKBRL2 antibody, CY6 antibody, GPRCY6 antibody, TER1 antibody, C-C antibody, C-C CKR-8 antibody, CKR-8 antibody, Cmkbr8 antibody, mCCR8 antibody, C-C motif chemokine receptor 8 antibody, chemokine (C-C motif) receptor 8 antibody, CCR8 antibody, Ccr8 antibody
- 背景
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This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptors are important for the migration of various cell types into the inflammatory sites. This receptor protein preferentially expresses in the thymus. I-309, thymus activation-regulated cytokine (TARC) and macrophage inflammatory protein-1 beta (MIP-1 beta) have been identified as ligands of this receptor. Studies of this receptor and its ligands suggested its role in regulation of monocyte chemotaxis and thymic cell apoptosis. More specifically, this receptor may contribute to the proper positioning of activated T cells within the antigenic challenge sites and specialized areas of lymphoid tissues. This gene is located at the chemokine receptor gene cluster region.
Cellular Localization: Cell membrane - 分子量
- 41 kDa
- 基因ID
- 1237
- UniProt
- P51685
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