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ADRA2C 抗体 (C-Term)

ADRA2C 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2854717
发货至: 中国
  • 抗原 See all ADRA2C 抗体
    ADRA2C (Adrenergic, alpha-2C-, Receptor (ADRA2C))
    抗原表位
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    C-Term
    适用
    • 82
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    宿主
    • 59
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    克隆类型
    • 59
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    多克隆
    标记
    • 31
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    This ADRA2C antibody is un-conjugated
    应用范围
    • 55
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    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    交叉反应
    产品特性
    Rabbit Polyclonal antibody to alpha 2c Adrenergic Receptor (adrenergic, alpha-2C-, receptor)
    alpha 2c Adrenergic Receptor antibody [C2C3], C-term
    纯化方法
    Purified by antigen-affinity chromatography.
    免疫原
    Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human alpha 2c Adrenergic Receptor. The exact sequence is proprietary.
    亚型
    IgG
    Top Product
    Discover our top product ADRA2C Primary Antibody
  • 应用备注
    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    说明

    Positive Control: HeLa

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.62 mg/mL
    缓冲液
    0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
    储存液
    Thimerosal (Merthiolate)
    注意事项
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原
    ADRA2C (Adrenergic, alpha-2C-, Receptor (ADRA2C))
    别名
    adrenoceptor alpha 2C (ADRA2C 产品)
    别名
    ADRA2L2 antibody, ADRA2RL2 antibody, ADRARL2 antibody, ALPHA2CAR antibody, Adra-2c antibody, [a]2C antibody, alpha2-C4 antibody, alpha2C antibody, zgc:194523 antibody, zgc:194541 antibody, adra2c antibody, ADRA2B antibody, ADRA2C antibody, adrenoceptor alpha 2C antibody, adrenergic receptor, alpha 2c antibody, ADRA2C antibody, Adra2c antibody, adra2c antibody
    背景
    Alpha-2-adrenergic receptors are members of the G protein-coupled receptor superfamily. They include 3 highly homologous subtypes: alpha2A, alpha2B, and alpha2C. These receptors have a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. The mouse studies revealed that both the alpha2A and alpha2C subtypes were required for normal presynaptic control of transmitter release from sympathetic nerves in the heart and from central noradrenergic neurons. The alpha2A subtype inhibited transmitter release at high stimulation frequencies, whereas the alpha2C subtype modulated neurotransmission at lower levels of nerve activity. This gene encodes the alpha2C subtype, which contains no introns in either its coding or untranslated sequences.

    Cellular Localization: Cell membrane
    分子量
    50 kDa
    基因ID
    152
    UniProt
    P18825
    途径
    EGFR Signaling Pathway, cAMP Metabolic Process
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