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CISH 抗体 (C-Term)

CISH 适用: 人 WB, ICC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2854656
发货至: 中国
  • 抗原 See all CISH 抗体
    CISH (Cytokine Inducible SH2-Containing Protein (CISH))
    抗原表位
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 24
    • 17
    • 15
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    宿主
    • 24
    • 1
    克隆类型
    • 25
    多克隆
    标记
    • 18
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CISH antibody is un-conjugated
    应用范围
    • 15
    • 6
    • 5
    • 4
    • 4
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    交叉反应
    人, 大鼠
    产品特性
    Rabbit Polyclonal antibody to CIS (cytokine inducible SH2-containing protein)
    CIS antibody [C2C3], C-term
    纯化方法
    Purified by antigen-affinity chromatography.
    免疫原
    Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human CIS. The exact sequence is proprietary.
    亚型
    IgG
  • 应用备注
    WB: 1:1000-1:10000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    说明

    Positive Control: HeLa , PC-12 , Rat2

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    1XPBS ( pH 7), 20 % Glycerol, 0.01 % Thimerosal
    储存液
    Thimerosal (Merthiolate)
    注意事项
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原
    CISH (Cytokine Inducible SH2-Containing Protein (CISH))
    别名
    cytokine inducible SH2 containing protein (CISH 产品)
    别名
    CISH antibody, cis antibody, cish.a antibody, ptk9l antibody, twf1l antibody, wu:fk57g04 antibody, zgc:154062 antibody, zgc:91817 antibody, g18 antibody, socs antibody, cis-1 antibody, cish antibody, BACTS2 antibody, CIS antibody, CIS-1 antibody, G18 antibody, SOCS antibody, AI385595 antibody, CIS1 antibody, Cis antibody, F17 antibody, F23 antibody, cytokine inducible SH2 containing protein antibody, cytokine inducible SH2-containing protein antibody, CISH antibody, cish antibody, Cish antibody
    背景
    The protein encoded by this gene contains a SH2 domain and a SOCS box domain. The protein thus belongs to the cytokine-induced STAT inhibitor (CIS), also known as suppressor of cytokine signaling (SOCS) or STAT-induced STAT inhibitor (SSI), protein family. CIS family members are known to be cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by IL2, IL3, GM-CSF and EPO in hematopoietic cells. Proteasome-mediated degradation of this protein has been shown to be involved in the inactivation of the erythropoietin receptor. Multiple transcript variants encoding different isoforms have been found for this gene.

    分子量
    29 kDa
    基因ID
    1154
    UniProt
    Q9NSE2
    途径
    JAK/STAT Signaling, Response to Growth Hormone Stimulus
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