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Caveolin-1 抗体 (N-Term)

Name: Caveolin-1 抗体 (N-Term)
Brand: antibodies-online
SKU: ABIN2854651
Availability: OutOfStock

KO Validated CAV1 适用: 人 WB, IF, IP, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated

WB Image Caveolin 1 antibody [N1N3] detects Caveolin 1 protein by western blot analysis. (Caveolin-1 抗体 (N-Term))

WB Image Caveolin 1 antibody detects Caveolin 1 protein by western blot analysis. (Caveolin-1 抗体 (N-Term))

IP Image Immunoprecipitation of Caveolin 1 protein from A549 membrane extracts using 5 μg of Caveolin 1 antibody [N1N3], Western blot analysis was performed using Caveolin 1 antibody [N1N3], EasyBlot anti-Rabbit IgG was used as a secondary reagent. (Caveolin-1 抗体 (N-Term))

IHC-P Image Immunohistochemical microscopy analysis of paraffin-embedded lung carcinoma cell line xenograft tissue using Caveolin-1 antibody [N1N3] , (1:100). (Caveolin-1 抗体 (N-Term))

IHC

ICC/IF Image Caveolin 1 antibody [N1N3] detects Caveolin 1 protein at membrane by immunofluorescent analysis. (Caveolin-1 抗体 (N-Term))

Down-regulation of caveolae number and Caveolin1-3 expressions in DCP bladder ICCs-DM. (Caveolin-1 抗体 (N-Term))

Metastatic ovarian cancer cells enhance c-Kit, Notch3, and membrane raft-associated PHB and contribute to CSC enrichment. (Caveolin-1 抗体 (N-Term))

7 images

(1 reference)

产品编号 ABIN2854651

发货至: 中国

Datasheet as PDF

抗原 See all Caveolin-1 (CAV1) 抗体

Caveolin-1 (CAV1) (Caveolin 1, Caveolae Protein, 22kDa (CAV1))
抗原表位
15

13

8

7

4

4

4

4

4

3

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1
N-Term
适用
104

64

50

12

10

9

9

8

8

7

5

3

2

1

1

1

1

1

1

1

1

1

1
人
宿主
95

10

6

2
兔
Compatible Secondaries
克隆类型
94

19
多克隆
标记
78

7

3

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1
This Caveolin-1 antibody is un-conjugated
应用范围
88

36

27

19

19

16

16

15

11

8

4

3

2

1
Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

交叉反应

人, 小鼠, 大鼠

产品特性

Rabbit polyclonal antibody to Caveolin 1 (caveolin 1, caveolae protein, 22 kDa)
Caveolin 1 antibody [N1N3]

纯化方法

Purified by antigen-affinity chromatography.

质量等级

KO Validated

免疫原

Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human Caveolin 1. The exact sequence is proprietary.

亚型

IgG
anti-Caveolin 1, Caveolae Protein, 22kDa (CAV1) (AA 2-104) antibody
CAV1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Caveolin 1, Caveolae Protein, 22kDa (CAV1) (AA 2-104) antibody
CAV1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Caveolin 1, Caveolae Protein, 22kDa (CAV1) (AA 2-105) antibody
CAV1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Caveolin 1, Caveolae Protein, 22kDa (CAV1) (Internal Region) antibody
Verified CAV1 适用: 人 WB, ELISA, IHC, IF, FACS 宿主: 山羊 Polyclonal unconjugated

anti-Caveolin 1, Caveolae Protein, 22kDa (CAV1) (AA 1-100) antibody
CAV1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Caveolin 1, Caveolae Protein, 22kDa (CAV1) (AA 2-120) antibody
CAV1 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro), FACS 宿主: 兔 Polyclonal unconjugated

anti-Caveolin 1, Caveolae Protein, 22kDa (CAV1) (AA 4-178) antibody
CAV1 适用: 人, 小鼠 WB, IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Caveolin 1, Caveolae Protein, 22kDa (CAV1) (AA 4-178) antibody
CAV1 适用: 人, 小鼠 WB, IF, IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Caveolin 1, Caveolae Protein, 22kDa (CAV1) (N-Term) antibody
CAV1 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Caveolin 1, Caveolae Protein, 22kDa (CAV1) (pTyr14) antibody
CAV1 适用: 人, 大鼠, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

应用备注

WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

说明

Positive Control: A431 , H1299 , HeLa , mouse lung , HeLa
Validation: KO/KD, Orthogonal

限制

仅限研究用
状态

Liquid

浓度

1 mg/mL

缓冲液

1XPBS ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

储存液

Thimerosal (Merthiolate)

注意事项

This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
Fang, Lin, Liang, Liang: "A novel c-Kit/phospho-prohibitin axis enhances ovarian cancer stemness and chemoresistance via Notch3-PBX1 and β-catenin-ABCG2 signaling." in: Journal of biomedical science, Vol. 27, Issue 1, pp. 42, (2020) (PubMed).
抗原

Caveolin-1 (CAV1) (Caveolin 1, Caveolae Protein, 22kDa (CAV1))

别名

caveolin 1 (CAV1 产品)

别名

fc07c04 antibody, wu:fc07c04 antibody, Cav-1 antibody, bscl3 antibody, cav1 antibody, cav1a antibody, cgl3 antibody, vip21 antibody, cav1b antibody, caveolin-1 antibody, cav antibody, mstp085 antibody, Caveolin-1 antibody, CAV1 antibody, cav-1 antibody, Cav antibody, caveolin 1 antibody, BSCL3 antibody, CGL3 antibody, MSTP085 antibody, PPH3 antibody, VIP21 antibody, caveolin 1 antibody, caveolin 1 L homeolog antibody, caveolin 1 S homeolog antibody, caveolin 1, caveolae protein antibody, caveolin 1, caveolae protein, 22kDa antibody, Caveolin antibody, cav1 antibody, cav1.L antibody, cav1.S antibody, CAV1 antibody, Cav1 antibody, cav-1 antibody

背景

The scaffolding protein encoded by this gene is the main component of the caveolae plasma membranes found in most cell types. The protein links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression. The gene is a tumor suppressor gene candidate and a negative regulator of the Ras-p42/44 MAP kinase cascade. CAV1 and CAV2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. By using alternative initiation codons in the same reading frame, two isoforms (alpha and beta) are encoded by a single transcript from this gene.

Cellular Localization: Golgi apparatus membrane , Cell membrane , Membrane , caveola

分子量

20 kDa

基因ID

857

UniProt

Q03135

途径

Maintenance of Protein Location, Signaling Events mediated by VEGFR1 and VEGFR2, Negative Regulation of Transporter Activity, VEGFR1 Specific Signals