DUSP14 抗体 (C-Term)
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- 抗原 See all DUSP14 抗体
- DUSP14 (Dual Specificity Phosphatase 14 (DUSP14))
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抗原表位
- C-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This DUSP14 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 交叉反应
- 人
- 产品特性
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Rabbit polyclonal antibody to MKP-6 (dual specificity phosphatase 14)
MKP-6 antibody [C2C3], C-term - 纯化方法
- Affinity purified by Protein A.
- 免疫原
- Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human DUSP14. The exact sequence is proprietary.
- 亚型
- IgG
- Top Product
- Discover our top product DUSP14 Primary Antibody
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- 应用备注
- WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- 说明
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Positive Control: MKP-6 transfected 293T
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 2 mg/mL
- 缓冲液
- 1XPBS ( pH 7), 40 % Glycerol, 0.01 % Thimerosal
- 储存液
- Thimerosal (Merthiolate)
- 注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- 抗原
- DUSP14 (Dual Specificity Phosphatase 14 (DUSP14))
- 别名
- dual specificity phosphatase 14 (DUSP14 产品)
- 别名
- MGC84083 antibody, zgc:101746 antibody, DUSP14 antibody, mkp-l antibody, mkp6 antibody, MKP-L antibody, MKP6 antibody, 1110014C10Rik antibody, 2310042C07Rik antibody, D11Ertd395e antibody, Mkp6 antibody, dual specificity phosphatase 14 antibody, dual specificity phosphatase 14 L homeolog antibody, DUSP14 antibody, dusp14.L antibody, dusp14 antibody, Dusp14 antibody
- 背景
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In addition to antigen recognition by the T-cell receptor, T-cell activation requires a second signal from a costimulatory receptor, such as CD28 (MIM 186760), which interacts with B7-1 (CD80, MIM 112203) and B7-2 (CD86, MIM 601020) ligands on antigen-presenting cells. CD28 costimulation induces transcription of interleukin-2 (IL2, MIM 147680) and stabilizes newly synthesized IL2 through the activation of mitogen-activated protein kinases (MAPKs), such as ERK (e.g., MAP2K4, MIM 601335) and JNK (see MIM 601158), and the subsequent creation of AP1 transcription factor (see MIM 165160). DUSP14 is a negative regulator of CD28 signaling.[supplied by OMIM]
- 分子量
- 22 kDa
- 基因ID
- 11072
- UniProt
- O95147
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