ZAK 抗体
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- 抗原 See all ZAK 抗体
- ZAK (Mitogen-Activated Protein Kinase Kinase Kinase MLT (ZAK))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ZAK antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 交叉反应
- 人
- 产品特性
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Rabbit polyclonal antibody to ZAK
ZAK antibody [N3C2], Internal - 纯化方法
- Purified by antigen-affinity chromatography.
- 质量等级
- KO Validated
- 免疫原
- Recombinant protein encompassing a sequence within the center region of human ZAK. The exact sequence is proprietary.
- 亚型
- IgG
- Top Product
- Discover our top product ZAK Primary Antibody
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- 应用备注
- WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- 说明
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Positive Control: HeLa
Validation: KO/KD
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.92 mg/mL
- 缓冲液
- 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
- 储存液
- Thimerosal (Merthiolate)
- 注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- 抗原
- ZAK (Mitogen-Activated Protein Kinase Kinase Kinase MLT (ZAK))
- 别名
- mitogen-activated protein kinase kinase kinase 20 (ZAK 产品)
- 别名
- MLTK antibody, RGD1561394 antibody, AZK antibody, MLK7 antibody, MLT antibody, MRK antibody, mlklak antibody, pk antibody, AV006891 antibody, B230120H23Rik antibody, MLTKalpha antibody, MLTKbeta antibody, mitogen-activated protein kinase kinase kinase 20 antibody, Map3k20 antibody, MAP3K20 antibody
- 背景
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This gene is a member of the MAPKKK family of signal transduction molecules and encodes a protein with an N-terminal kinase catalytic domain, followed by a leucine zipper motif and a sterile-alpha motif (SAM). This magnesium-binding protein forms homodimers and is located in the cytoplasm. The protein mediates gamma radiation signaling leading to cell cycle arrest and activity of this protein plays a role in cell cycle checkpoint regulation in cells. The protein also has pro-apoptotic activity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Cellular Localization: Cytoplasm , Nucleus - 分子量
- 91 kDa
- 基因ID
- 51776
- UniProt
- Q9NYL2
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