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- 抗原 See all Aconitase 1 (ACO1) 抗体
- Aconitase 1 (ACO1)
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Aconitase 1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)
- 交叉反应
- 人
- 产品特性
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Rabbit Polyclonal antibody to Aconitase 1 (aconitase 1, soluble)
Aconitase 1 antibody [N1C1] - 纯化方法
- Purified by antigen-affinity chromatography.
- 免疫原
- Recombinant protein encompassing a sequence within the center region of human Aconitase 1. The exact sequence is proprietary.
- 亚型
- IgG
- Top Product
- Discover our top product ACO1 Primary Antibody
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anti-Aconitase 1 (ACO1) (AA 251-443) antibody
ACO1 适用: 人 WB, ELISA, IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Aconitase 1 (ACO1) (AA 329-443) antibodyACO1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Aconitase 1 (ACO1) (N-Term) antibodyACO1 适用: 人, 小鼠, 大鼠, Cow, 兔, 犬, 豚鼠, 马, Pig WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Aconitase 1 (ACO1) (AA 26-243) antibodyACO1 适用: 人 WB, ELISA, IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Aconitase 1 (ACO1) (AA 508-745) antibodyACO1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Aconitase 1 (ACO1) (AA 1-889) antibodyACO1 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Aconitase 1 (ACO1) (AA 780-889) antibodyACO1 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 2C1 unconjugated
anti-Aconitase 1 (ACO1) antibodyACO1 适用: 人, 小鼠, 大鼠, Hamster WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Aconitase 1 (ACO1) (AA 527-719) antibodyACO1 适用: 小鼠 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Aconitase 1 (ACO1) (AA 1-889) antibodyACO1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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- 应用备注
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- 说明
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Positive Control: A431 , HeLa , HepG2
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.78 mg/mL
- 缓冲液
- 0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal
- 储存液
- Thimerosal (Merthiolate)
- 注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- 抗原
- Aconitase 1 (ACO1)
- 别名
- aconitase 1 (ACO1 产品)
- 别名
- ACONS antibody, IREB1 antibody, IREBP antibody, IREBP1 antibody, IRP1 antibody, Acon1 antibody, Ratireb antibody, ratireb antibody, Aco1 antibody, AI256519 antibody, Aco-1 antibody, Irebp antibody, Irp1 antibody, aconitase 1 antibody, aconitase 1, soluble antibody, aconitase 1 L homeolog antibody, ACO1 antibody, Aco1 antibody, aco1.L antibody
- 背景
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Aconitase 1, also known as iron regulatory element binding protein 1 (IREB1), is a cytosolic protein which binds to iron-responsive elements (IREs). IREs are stem-loop structures found in the 5' UTR of ferritin mRNA, and in the 3' UTR of transferrin receptor mRNA. The iron-induced binding to the IRE results in repression of translation of ferritin mRNA, and inhibition of degradation of the otherwise rapidly degrading transferrin receptor mRNA. Thus, IREB1 plays a central role in cellular iron homeostasis. It was also shown to have aconitase activity, and hence grouped with the aconitase family of enzymes.
Cellular Localization: Cytoplasm - 分子量
- 98 kDa
- 基因ID
- 48
- UniProt
- P21399
- 途径
- Transition Metal Ion Homeostasis
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