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- 抗原 See all LIG1 抗体
- LIG1 (Ligase I, DNA, ATP-Dependent (LIG1))
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抗原表位
- C-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This LIG1 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 交叉反应
- 人
- 产品特性
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Rabbit polyclonal antibody to DNA ligase I (ligase I, DNA, ATP-dependent)
DNA ligase I antibody [C2C3], C-term - 纯化方法
- Purified by antigen-affinity chromatography.
- 免疫原
- Recombinant protein encompassing a sequence within the C-terminus region of human DNA ligase I. The exact sequence is proprietary.
- 亚型
- IgG
- Top Product
- Discover our top product LIG1 Primary Antibody
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- 应用备注
- WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- 说明
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Positive Control: A431 , H1299
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
- 储存液
- Thimerosal (Merthiolate)
- 注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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DNA Ligase 1 is an essential mediator of sister chromatid telomere fusions in G2 cell cycle phase." in: Nucleic acids research, Vol. 47, Issue 5, pp. 2402-2424, (2019) (PubMed).
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DNA Ligase 1 is an essential mediator of sister chromatid telomere fusions in G2 cell cycle phase." in: Nucleic acids research, Vol. 47, Issue 5, pp. 2402-2424, (2019) (PubMed).
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- 抗原
- LIG1 (Ligase I, DNA, ATP-Dependent (LIG1))
- 别名
- DNA ligase 1 (LIG1 产品)
- 别名
- ATLIG1 antibody, DNA ligase 1 antibody, T6D22.23 antibody, ligI antibody, AL033288 antibody, LigI antibody, lig1 antibody, wu:fc54a11 antibody, DNA ligase 1 antibody, DNA ligase 1, putative antibody, ligase I, DNA, ATP-dependent L homeolog antibody, ligase I, DNA, ATP-dependent antibody, LIG1 antibody, PB000674.02.0 antibody, PTRG_06243 antibody, PKH_140260 antibody, lig1.L antibody, Lig1 antibody, lig-1 antibody, lig1 antibody
- 背景
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LIG1 encodes DNA ligase I, with functions in DNA replication and the base excision repair process. Mutations in LIG1 that lead to DNA ligase I deficiency result in immunodeficiency and increased sensitivity to DNA-damaging agents.
Cellular Localization: Nucleus - 分子量
- 102 kDa
- 基因ID
- 3978
- UniProt
- P18858
- 途径
- Telomere Maintenance, DNA Damage Repair, DNA Replication, Synthesis of DNA
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