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FAP 抗体

FAP 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2854402
发货至: 中国
  • 抗原 See all FAP 抗体
    FAP (Fibroblast Activation Protein, alpha (FAP))
    适用
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    宿主
    • 62
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    克隆类型
    • 61
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    多克隆
    标记
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    This FAP antibody is un-conjugated
    应用范围
    • 56
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    Western Blotting (WB)
    交叉反应
    产品特性
    Rabbit polyclonal antibody to FAP (fibroblast activation protein, alpha)
    FAP antibody [N1N3]
    纯化方法
    Purified by antigen-affinity chromatography.
    免疫原
    Recombinant protein encompassing a sequence within the center region of human FAP. The exact sequence is proprietary.
    亚型
    IgG
    Top Product
    Discover our top product FAP Primary Antibody
  • 应用备注
    WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    说明

    Positive Control: HepG2 , Molt-4

    Validation: Orthogonal

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.58 mg/mL
    缓冲液
    0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
    储存液
    Thimerosal (Merthiolate)
    注意事项
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Wolczyk, Zaremba-Czogalla, Hryniewicz-Jankowska, Tabola, Grabowski, Sikorski, Augoff: "TNF-α promotes breast cancer cell migration and enhances the concentration of membrane-associated proteases in lipid rafts." in: Cellular oncology (Dordrecht), Vol. 39, Issue 4, pp. 353-63, (2017) (PubMed).

  • 抗原
    FAP (Fibroblast Activation Protein, alpha (FAP))
    别名
    fibroblast activation protein alpha (FAP 产品)
    别名
    fap-A antibody, gene 13 antibody, FAP antibody, fapa antibody, dppiv antibody, seprase antibody, DPPIV antibody, FAPA antibody, fibroblast activation protein antibody, fibroblast activation protein alpha L homeolog antibody, fibroblast activation protein alpha antibody, fibroblast activation protein, alpha antibody, prolyl endopeptidase FAP antibody, Fap antibody, fap.L antibody, FAP antibody, fap antibody, LOC100547273 antibody
    背景
    The protein encoded by this gene is a homodimeric integral membrane gelatinase belonging to the serine protease family. It is selectively expressed in reactive stromal fibroblasts of epithelial cancers, granulation tissue of healing wounds, and malignant cells of bone and soft tissue sarcomas. This protein is thought to be involved in the control of fibroblast growth or epithelial-mesenchymal interactions during development, tissue repair, and epithelial carcinogenesis.

    Cellular Localization: Cell membrane, Single-pass type II membrane protein , Cell projection , lamellipodium membrane, Single-pass type II membrane protein , invadopodium membrane, Single-pass type II membrane protein
    分子量
    88 kDa
    基因ID
    2191
    UniProt
    Q12884
    途径
    Tube Formation
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