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ILK 抗体

KO Validated ILK 适用: 人 WB, IHC, IHC (p), IP, IHC (wm) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2854345
发货至: 中国
  • 抗原 See all ILK 抗体
    ILK (Integrin-Linked Kinase (ILK))
    适用
    • 146
    • 59
    • 52
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    • 1
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    • 1
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    宿主
    • 155
    • 5
    • 1
    克隆类型
    • 155
    • 6
    多克隆
    标记
    • 60
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    • 3
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    This ILK antibody is un-conjugated
    应用范围
    • 108
    • 87
    • 53
    • 40
    • 39
    • 19
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    • 4
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    Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Immunohistochemistry (Whole Mount) (IHC (wm))
    交叉反应
    人, 小鼠, 大鼠, 斑马鱼
    产品特性
    Rabbit Polyclonal antibody to CKR5 (integrin-linked kinase)
    ILK antibody [N1C1]
    纯化方法
    Purified by antigen-affinity chromatography.
    质量等级
    KO Validated
    免疫原
    Recombinant protein encompassing a sequence within the center region of human ILK. The exact sequence is proprietary.
    亚型
    IgG
  • 应用备注
    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    说明

    Positive Control: A431 , Neuro2A , C8D30 , NIH-3T3 , C2Cl2 , PC-12 , Neuro 2A , C8D30 , Raw264.7 , HeLa

    Validation: KO/KD

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.8 mg/mL
    缓冲液
    0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
    储存液
    Thimerosal (Merthiolate)
    注意事项
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Yen, Hsiao, Jiang, Chang, Wang, Shen, Chen, Chang, Chang, Chen et al.: "Insulin-like growth factor-independent insulin-like growth factor binding protein 3 promotes cell migration and lymph node metastasis of oral squamous cell carcinoma cells by requirement of integrin ..." in: Oncotarget, Vol. 6, Issue 39, pp. 41837-55, (2016) (PubMed).

  • 抗原
    ILK (Integrin-Linked Kinase (ILK))
    别名
    integrin linked kinase (ILK 产品)
    别名
    CG10504 antibody, CT29478 antibody, DmILK antibody, Dmel\\CG10504 antibody, ILK antibody, ilk antibody, l(3)78Ca antibody, p59 antibody, AA511515 antibody, ESTM24 antibody, zgc:65842 antibody, ILK-1 antibody, ILK-2 antibody, P59 antibody, p59ILK antibody, Integrin linked kinase antibody, integrin linked kinase antibody, integrin linked kinase S homeolog antibody, integrin-linked protein kinase antibody, integrin-linked kinase antibody, Ilk antibody, ILK antibody, ilk.S antibody, CpipJ_CPIJ016644 antibody, Bm1_20815 antibody, Tsp_07213 antibody, Tsp_07224 antibody, Tsp_15354 antibody, ilk antibody
    背景
    Transduction of extracellular matrix signals through integrins influences intracellular and extracellular functions, and appears to require interaction of integrin cytoplasmic domains with cellular proteins. Integrin-linked kinase (ILK), interacts with the cytoplasmic domain of beta-1 integrin. This gene encodes a serine/threonine protein kinase with 4 ankyrin-like repeats, which associates with the cytoplasmic domain of beta integrins and acts as a proximal receptor kinase regulating integrin-mediated signal transduction. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene.

    Cellular Localization: Cell junction , focal adhesion , Cell membrane, Peripheral membrane protein, Cytoplasmic side
    分子量
    51 kDa
    基因ID
    3611
    UniProt
    Q13418
    途径
    Regulation of Muscle Cell Differentiation, Regulation of Cell Size, Maintenance of Protein Location, Skeletal Muscle Fiber Development, Smooth Muscle Cell Migration
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