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NOTCH2 抗体 (C-Term)

Name: NOTCH2 抗体 (C-Term)
Brand: antibodies-online
SKU: ABIN2854343
Availability: OutOfStock

NOTCH2 适用: 人, 小鼠 WB, ChIP-seq 宿主: 兔 Polyclonal unconjugated

WB Image Sample (30 ug of whole cell lysate) A:NIH-3T3 5% SDS PAGE antibody diluted at 1:1000 (NOTCH2 抗体 (C-Term))

WB Image Sample (30 ug of whole cell lysate) A: Hela 5% SDS PAGE antibody diluted at 1:1000 (NOTCH2 抗体 (C-Term))

2 images

(1 reference)

产品编号 ABIN2854343

发货至: 中国

Datasheet as PDF

抗原 See all NOTCH2 抗体

NOTCH2 (Notch 2 (NOTCH2))
抗原表位
16

15

5

4

3

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
C-Term
适用
67

49

30

5

4

4

2

1

1

1

1

1
人, 小鼠
宿主
74

5

3

1

1
兔
Compatible Secondaries
克隆类型
73

8

2
多克隆
标记
40

4

4

3

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1
This NOTCH2 antibody is un-conjugated
应用范围
47

32

26

26

19

14

11

11

7

6

3

2

2

1
Western Blotting (WB), ChIP DNA-Sequencing (ChIP-seq)

交叉反应

大鼠

交叉反应（详细）

Rat (89 %)

产品特性

Rabbit polyclonal antibody to NOTCH2 (Notch homolog 2 (Drosophila))
NOTCH2 antibody [C2], C-term

纯化方法

Purified by antigen-affinity chromatography.

免疫原

Recombinant protein encompassing a sequence within the C-terminus region of human NOTCH2. The exact sequence is proprietary.

亚型

IgG

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anti-Notch 2 (NOTCH2) (N-Term) antibody
NOTCH2 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Notch 2 (NOTCH2) (Asp1733), (cleaved) antibody
NOTCH2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-Notch 2 (NOTCH2) (AA 1501-1700) antibody
NOTCH2 适用: 人, 小鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Notch 2 (NOTCH2) (Cleaved-Asp1733) antibody
NOTCH2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-Notch 2 (NOTCH2) (AA 59-250) antibody
NOTCH2 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Notch 2 (NOTCH2) (AA 2251-2466) antibody
NOTCH2 适用: 人 WB, ELISA, IHC (p), IHC (fro), ICC 宿主: 兔 Polyclonal unconjugated

anti-Notch 2 (NOTCH2) (AA 2242-2471) antibody
NOTCH2 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated

anti-Notch 2 (NOTCH2) (Cleaved-Ala1734) antibody
NOTCH2 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Notch 2 (NOTCH2) antibody
NOTCH2 适用: 人, 小鼠 ELISA, IF, BP 宿主: 兔 Chimeric B6 unconjugated Recombinant Antibody

anti-Notch 2 (NOTCH2) (AA 27-136) antibody
NOTCH2 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated

应用备注

Suggested dilution Reference Western blot 1:500-1:3000* ChIP-sequencing Assay-dependent dilution Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceWestern blot1:500-1:3000* ChIP-sequencingAssay-dependent dilution

说明

Positive Control: A431 , HeLa , HepG2

限制

仅限研究用
状态

Liquid

浓度

1 mg/mL

缓冲液

1XPBS, 40 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

储存液

Thimerosal (Merthiolate)

注意事项

This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

-20 °C

储存方法

Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
Lin, Xie, Lin, Fu, Su, Tong, Chen, Wang, Zhao, Xia, Zhang, Zhang: "Epistatic Association of CD14 and NOTCH2 Genetic Polymorphisms with Biliary Atresia in a Southern Chinese Population." in: Molecular therapy. Nucleic acids, Vol. 13, pp. 590-595, (2018) (PubMed).
抗原

NOTCH2 (Notch 2 (NOTCH2))

别名

NOTCH2 (NOTCH2 产品)

别名

AGS2 antibody, HJCYS antibody, hN2 antibody, AI853703 antibody, N2 antibody, notch6 antibody, sb:cb884 antibody, neurogenic locus notch homolog protein 2 antibody, notch 2 antibody, notch 3 antibody, LOC581186 antibody, NOTCH2 antibody, notch3 antibody, Notch2 antibody, notch2 antibody

背景

This gene encodes a member of the Notch family. Members of this Type 1 transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain consisting of multiple, different domain types. Notch family members play a role in a variety of developmental processes by controlling cell fate decisions. The Notch signaling network is an evolutionarily conserved intercellular signaling pathway which regulates interactions between physically adjacent cells. In Drosophilia, notch interaction with its cell-bound ligands (delta, serrate) establishes an intercellular signaling pathway that plays a key role in development. Homologues of the notch-ligands have also been identified in human, but precise interactions between these ligands and the human notch homologues remain to be determined. This protein is cleaved in the trans-Golgi network, and presented on the cell surface as a heterodimer. This protein functions as a receptor for membrane bound ligands, and may play a role in vascular, renal and hepatic development.

Cellular Localization: Cell membrane, Single-pass type I membrane protein , Notch 2 intracellular domain: Nucleus

分子量

265 kDa

基因ID

4853

途径

Notch Signaling, Stem Cell Maintenance