Prostate Specific Antigen 抗体
-
- 抗原 See all Prostate Specific Antigen (PSA) 抗体
- Prostate Specific Antigen (PSA)
-
适用
- 人
-
宿主
- 小鼠
-
克隆类型
- 单克隆
-
标记
- This Prostate Specific Antigen antibody is un-conjugated
-
应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA)
- 特异性
- This antibody detects normal prostate, benign prostate hyperplasia and prostate malignant carcinoma.
- 纯化方法
- Affinity Chromatography on Protein G
- 免疫原
- Human Prostate Specific Antigen
- 克隆位点
- CHYH2
- 亚型
- IgG1
- Top Product
- Discover our top product PSA Primary Antibody
-
-
- 应用备注
-
ELISA. Western blot: Concentration of 10 μg/mL MAb will allow visualization of 1 μg/lane of humanPSA. Immunohistochemistry-formalin-fixed paraffin embedded and frozen tissue sections usingABC immunoperoxidase assay.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
-
- 溶解方式
- Restore with double distillated water to a final concentration to 1.0 mg/mL.
- 缓冲液
- 0.01 M PBS, pH 7.0 without preservatives
- 储存液
- Without preservative
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store the antibody prior to reconstitution at -20 °C. Following reconstitution the antibody can be stored at 2-8 °C for one month or at -20 °C for longer.
-
- 抗原
- Prostate Specific Antigen (PSA)
- 别名
- Kallikrein-3 / PSA / KLK3 (PSA 产品)
- 背景
- Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its protein product is a protease present in seminal plasma. It is thought to function normally in the liquefaction of seminal coagulum, presumably by hydrolysis of the high molecular mass seminal vesicle protein. Serum level of this protein, called PSA in the clinical setting, is useful in the diagnosis and monitoring of prostatic carcinoma. Alternate splicing of this gene generates two transcript variants encoding different isoforms. Additional transcript variants have been described, but it is unclear if these transcripts are normally expressed or if they are specific to benign or malignant tumors.Synonyms: Gamma-seminoprotein, P-30 antigen, Prostate-specific antigen, Semenogelase
- 基因ID
- 354
- NCBI登录号
- NP_001025218
- UniProt
- P07288
- 途径
- Complement System
-