Cyclin A 抗体 (Biotin)
-
- 抗原 See all Cyclin A (CCNA2) 抗体
- Cyclin A (CCNA2) (Cyclin A2 (CCNA2))
-
适用
- 人, 小鼠, 大鼠
-
宿主
- 小鼠
-
克隆类型
- 单克隆
-
标记
- This Cyclin A antibody is conjugated to Biotin
-
应用范围
- Western Blotting (WB), Immunoprecipitation (IP)
- 特异性
- This antibody reacts with Cyclin A (55 kDa).
- 纯化方法
- Protein-A Agarose Chromatography of hybridoma supernatant.
- 免疫原
- Bovine recombinant Cyclin A.
- 克隆位点
- E67-1
- 亚型
- IgG2a
- Top Product
- Discover our top product CCNA2 Primary Antibody
-
-
- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
-
- 浓度
- 20 µg/mL
- 缓冲液
- PBS, pH 7.2 containing 1 % BSA as stabilizer and 0.09 % Sodium Azide as preservative.
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- -20 °C
- 储存方法
- Store the antibody (in aliquots) at -20 °C.
-
- 抗原
- Cyclin A (CCNA2) (Cyclin A2 (CCNA2))
- 别名
- Cyclin A2 (CCNA2 产品)
- 背景
- Cyclin A is a 60 kDa cyclin that binds both cdk2 and p34cdc2 (cdk1), giving two distinct cyclin A kinase activities, one appearing in G1/S phase, the other in G2/M. The level of cyclin A protein peaks in S-phase, and the activity of the cdk2-cyclin A complexes is essential for DNA replication and progression through S phase. Cyclin A is thus a marker for actively proliferating cells and for cells in S-phase. In normal cells, cdk2-cyclin A complexes associate with PCNA and p21CIPP1/WAF1. In addition, cyclin A has been implicated in cell transformation and is found in complexes with E1A, transcrIPPtion factors DRT F1 and E2F, and retinoblastoma protein, p110.Synonyms: CCN1, CCNA, CCNA2, Cyclin A, Cyclin-A2
- 基因ID
- 890
- NCBI登录号
- NP_001228
- UniProt
- P20248
- 途径
- PI3K-Akt Signaling, Cell Division Cycle, AMPK Signaling, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Synthesis of DNA
-