ATM 抗体 (C-Term)
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- 抗原 See all ATM 抗体
- ATM (Ataxia Telangiectasia Mutated (ATM))
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抗原表位
- C-Term
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ATM antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP), Immunofluorescence (IF), Flow Cytometry (FACS), Immunocytochemistry (ICC)
- 特异性
- Reacts with human and mouse ATM protein
- 纯化方法
- Antigen affinity purified
- 免疫原
- A fragment of human ATM protein expressed in E.coli. The fragment relates to the C-terminal region (within the last third of the protein sequence)
- Top Product
- Discover our top product ATM Primary Antibody
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- 应用备注
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Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only :
- ICC/IF : 1/100 - IP : 1/100 to 1/500 - WB : 1/500 to 1/1 000 - IHC: 1/100 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 2.5 mg/mL
- 缓冲液
- PBS, glycerol 50 % , Sodium azide 0.05 %
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C/-80 °C
- 储存方法
- Aliquot and store at -20°C or -80°C. Avoid freeze-thaw cycles.
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- 抗原
- ATM (Ataxia Telangiectasia Mutated (ATM))
- 别名
- Serine-Protein Kinase ATM (ATM 产品)
- 背景
- Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Involved in Cell cycle, DNA damage, DNA repair.
- 基因ID
- 472
- 途径
- p53 Pathway, Apoptosis, DNA Damage Repair, Inositol Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus
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