NLRP2 抗体
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- 抗原 See all NLRP2 抗体
- NLRP2 (NLR Family, Pyrin Domain Containing 2 (NLRP2))
- 适用
- 人, 小鼠, Hamster, 猴
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This NLRP2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP), Immunocytochemistry (ICC)
- 特异性
- Reacts with NBS1 from human, mouse, hamster and primate
- 纯化方法
- Antiserum
- 免疫原
- Partial length human NBS1 protein [Swiss-Prot# O60934].
- Top Product
- Discover our top product NLRP2 Primary Antibody
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- 应用备注
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Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only :
- ICC : 1/50 to 1/200 - IF : 1/200 - IP : 3 μL - WB : 1/1000 - 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- , Sodium azide 0.02 %
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C/-80 °C
- 储存方法
- Aliquot and store at -20°C or -80°C. Avoid freeze-thaw cycles.
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- 抗原
- NLRP2 (NLR Family, Pyrin Domain Containing 2 (NLRP2))
- 别名
- Nijmegen Breakage Syndrome 1 (NBS1) (NLRP2 产品)
- 别名
- CLR19.9 antibody, NALP2 antibody, NBS1 antibody, PAN1 antibody, PYPAF2 antibody, NLRP2 antibody, E330007A02Rik antibody, Nalp2 antibody, NLR family pyrin domain containing 2 antibody, NACHT, LRR and PYD domains-containing protein 2 antibody, NLR family pyrin domain containing 7 antibody, NLR family, pyrin domain containing 2 antibody, NLRP2 antibody, LOC100301026 antibody, LOC100387349 antibody, NLRP7 antibody, Nlrp2 antibody
- 背景
- The p95 gene (identical to NBS1 and nibrin) is a member of the hMre11/hRad50 double-strand break complex.This protein complex has been implicated in Nijmegen breakage syndrome, an autosomal recessive disorder marked by increased cancer incidence, cell cycle checkpoint deficits, and ionizing radiation sensitivity, thus revealing a direct molecular link between double-strand break repair and cell cycle checkpoint functions.
- 途径
- Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity, Inflammasome
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