Mre11 抗体
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- 抗原 See all Mre11 (MRE11A) 抗体
- Mre11 (MRE11A) (MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae) (MRE11A))
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适用
- 人, 大鼠, 小鼠, 小鸡, Hamster
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Mre11 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP), Immunocytochemistry (ICC), Flow Cytometry (FACS), Chromatin Immunoprecipitation (ChIP)
- 特异性
- Reacts with Mre11 from human, mouse, rat, chicken, hamster
- 纯化方法
- Antiserum
- 免疫原
- Full length human Mre11 protein.
- Top Product
- Discover our top product MRE11A Primary Antibody
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- 应用备注
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Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only :
- IF : 1/200 - IP : 3 μL - WB : 1/5000 - IHC: 1/10 to 1/200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- , Sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C/-80 °C
- 储存方法
- Aliquot and store at -20°C or -80°C. Avoid freeze-thaw cycles.
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- 抗原
- Mre11 (MRE11A) (MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae) (MRE11A))
- Abstract
- MRE11A 产品
- 别名
- wu:faa63d12 antibody, zgc:64018 antibody, Mre11 antibody, Mre11b antibody, ATLD antibody, HNGS1 antibody, MRE11 antibody, MRE11B antibody, MRE11 homolog A, double strand break repair nuclease antibody, MRE11 homolog, double strand break repair nuclease antibody, MRE11A homolog A, double strand break repair nuclease antibody, mre11a antibody, MRE11 antibody, Mre11a antibody
- 背景
- The hMre11-hRad50-NBS1 protein plays a central role in the human cellular DNA-Damage response, with recent studies indicating that these proteins help link DNA-damage detection to DNA-repair and cell cycle-checkpoint functions.This protein complex has been implicated in the activation of cell cycle-regulatory pathways, due to the fact that the NBS1 gene mutates in the chromosomal-instability syndrome, Nijmegen breakdown syndrome (NBS), which is characterized by increased cancer incidence, cell cycle checkpoint defects, and ionizing radiation sensitivity.
- UniProt
- P49959
- 途径
- DNA Damage Repair
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