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Mre11 抗体

MRE11A 适用: 人, 大鼠, 小鼠, 小鸡, Hamster WB, IHC, IF, IP, ICC, FACS, ChIP 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN363310
发货至: 中国
  • 抗原 See all Mre11 (MRE11A) 抗体
    Mre11 (MRE11A) (MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae) (MRE11A))
    适用
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    人, 大鼠, 小鼠, 小鸡, Hamster
    宿主
    • 93
    • 7
    克隆类型
    • 85
    • 15
    多克隆
    标记
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    • 5
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    This Mre11 antibody is un-conjugated
    应用范围
    • 73
    • 36
    • 26
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    • 15
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    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP), Immunocytochemistry (ICC), Flow Cytometry (FACS), Chromatin Immunoprecipitation (ChIP)
    特异性
    Reacts with Mre11 from human, mouse, rat, chicken, hamster
    纯化方法
    Antiserum
    免疫原
    Full length human Mre11 protein.
    Top Product
    Discover our top product MRE11A Primary Antibody
  • 应用备注

    Working dilution: Optimal dilution should be determined by the end user.
    The following are guidelines only :
    - IF : 1/200 - IP : 3 μL - WB : 1/5000 - IHC: 1/10 to 1/200

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    , Sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C/-80 °C
    储存方法
    Aliquot and store at -20°C or -80°C. Avoid freeze-thaw cycles.
  • 抗原
    Mre11 (MRE11A) (MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae) (MRE11A))
    Abstract
    MRE11A 产品
    别名
    wu:faa63d12 antibody, zgc:64018 antibody, Mre11 antibody, Mre11b antibody, ATLD antibody, HNGS1 antibody, MRE11 antibody, MRE11B antibody, MRE11 homolog A, double strand break repair nuclease antibody, MRE11 homolog, double strand break repair nuclease antibody, MRE11A homolog A, double strand break repair nuclease antibody, mre11a antibody, MRE11 antibody, Mre11a antibody
    背景
    The hMre11-hRad50-NBS1 protein plays a central role in the human cellular DNA-Damage response, with recent studies indicating that these proteins help link DNA-damage detection to DNA-repair and cell cycle-checkpoint functions.This protein complex has been implicated in the activation of cell cycle-regulatory pathways, due to the fact that the NBS1 gene mutates in the chromosomal-instability syndrome, Nijmegen breakdown syndrome (NBS), which is characterized by increased cancer incidence, cell cycle checkpoint defects, and ionizing radiation sensitivity.
    UniProt
    P49959
    途径
    DNA Damage Repair
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