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- 抗原 See all Klotho (KL) 抗体
- Klotho (KL)
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抗原表位
- AA 986-1012, C-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Klotho antibody is un-conjugated
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应用范围
- Western Blotting (WB), Flow Cytometry (FACS)
- 特异性
- This Klotho antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 983~1012 amino acids from the C-terminal region of human Klotho.
- 纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- 免疫原
- This Klotho antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 986-1012 AA from the C-terminal region of human Klotho.
- 克隆位点
- RB21226
- 亚型
- Ig Fraction
- Top Product
- Discover our top product KL Primary Antibody
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- 应用备注
- WB = 1:1000, FACS = 1:10-50
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.5 mg/mL
- 缓冲液
- PBS with 0.09 % (W/V) sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
- 有效期
- 6 months
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Decrease of Klotho in the kidney of streptozotocin-induced diabetic rats." in: Journal of biomedicine & biotechnology, Vol. 2010, pp. 513853, (2010) (PubMed).
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Decrease of Klotho in the kidney of streptozotocin-induced diabetic rats." in: Journal of biomedicine & biotechnology, Vol. 2010, pp. 513853, (2010) (PubMed).
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- 抗原
- Klotho (KL)
- 别名
- Klotho (KL 产品)
- 别名
- alpha-kl antibody, KL antibody, LOC100223456 antibody, klotho antibody, Klotho antibody, KL antibody, Kl antibody, kl antibody, LOC100533542 antibody
- 背景
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Klotho is a type-I membrane protein that is related to beta-glucosidases. Reduced production of this protein has been observed in patients with chronic renal failure (CRF), and this may be one of the factors underlying the degenerative processes (e.g., arteriosclerosis, osteoporosis, and skin atrophy) seen in CRF. Also, mutations within this protein have been associated with ageing and bone loss.
Synonyms: Klotho, Klotho peptide, KL - 分子量
- 116181 DA
- 基因ID
- 9365
- UniProt
- Q9UEF7
- 途径
- Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Hormone Activity, Growth Factor Binding
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