HCN3 抗体 (AbBy Fluor® 594)
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- 抗原 See all HCN3 抗体
- HCN3 (Hyperpolarization Activated Cyclic Nucleotide-Gated Potassium Channel 3 (HCN3))
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This HCN3 antibody is conjugated to AbBy Fluor® 594
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应用范围
- Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human HCN3
- 亚型
- IgG
- Top Product
- Discover our top product HCN3 Primary Antibody
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- 应用备注
- IF(IHC-P) 1:50-200
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- HCN3 (Hyperpolarization Activated Cyclic Nucleotide-Gated Potassium Channel 3 (HCN3))
- 别名
- HCN3 (HCN3 产品)
- 别名
- BCNG-4 antibody, Bcng4 antibody, Hac3 antibody, Hcn4 antibody, hyperpolarization activated cyclic nucleotide gated potassium channel 3 antibody, hyperpolarization-activated cyclic nucleotide-gated potassium channel 3 antibody, hyperpolarization-activated, cyclic nucleotide-gated K+ 3 antibody, HCN3 antibody, Hcn3 antibody
- 背景
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Synonyms: Hcn3, HCN3_HUMAN, hyperpolarization activated cyclic nucleotide-gated potassium channel 3, KIAA1535, potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3.
Background: Hyperpolarization-activated, cyclic nucleotide-binding channels (HCN) are voltage-gated cation channels that are activated by direct binding of intracellular cyclic nucleotides. The HCN family consists of four members (HCN1-4), each with a core transmembrane segment domain and a C-terminal 120 amino-acid cyclic nucleotide-binding domain motif. HCN channels are expressed in the brain, heart, thalamus and testis. The pacemaker properties of HCN channels contribute to spontaneous rhythmic activity in the brain and heart. HCN3 contains a segment characterized by a series of positively charged amino acids at every third position. This region designated S4 is likely to be the voltage sensor of the protein. In the brain, HCN3 and HCN4 exhibit subcortical distribution mainly concentrated in the hypothalamus and thalamus, respectively.
- 基因ID
- 57657
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