GBA3 抗体 (AA 151-250) (AbBy Fluor® 594)
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- 抗原 See all GBA3 抗体
- GBA3 (Glucosidase, Beta, Acid 3 (Cytosolic) (GBA3))
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抗原表位
- AA 151-250
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This GBA3 antibody is conjugated to AbBy Fluor® 594
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应用范围
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- 预测反应
- Human,Rat,Cow,Sheep,Pig,Horse
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human GBA3/CBG
- 亚型
- IgG
- Top Product
- Discover our top product GBA3 Primary Antibody
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- 应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- GBA3 (Glucosidase, Beta, Acid 3 (Cytosolic) (GBA3))
- 别名
- GBA3/CBG (GBA3 产品)
- 别名
- im:6912508 antibody, CBG antibody, CBGL1 antibody, GLUC antibody, KLRP antibody, glucosylceramidase beta 3 antibody, glucosidase, beta, acid 3 (gene/pseudogene) antibody, glucosidase, beta, acid 3 (cytosolic) antibody, cytosolic beta-glucosidase antibody, glucosylceramidase beta 3 (gene/pseudogene) antibody, Gba3 antibody, gba3 antibody, GBA3 antibody, LOC100344458 antibody
- 背景
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Synonyms: CBG, CBGL1, Cytosolic beta glucosidase, Cytosolic beta glucosidase like protein 1, Cytosolic beta-glucosidase, Cytosolic beta-glucosidase-like protein 1, GBA3, GBA3_HUMAN, GLUC, Glucosidase beta acid 3, Klotho related protein.
Background: CBG is a monomeric enzyme involved in the absorption and metabolism of flavonoid glucosides. CBG is found predominately in the liver, but is also located in tissues such as spleen, small intestine and kidney. Through its catalytic activity, CBG is able to hydrolyze a variety of glycosides including phytoestrogens, cyanogens, and flavonols. Although its catalytic activity extends to many dietary flavonoids, CBG has increased specificity for hydrophobic aglycones such as beta-D-glucoside and beta-D-galactoside. Hydrolysis is inhibited by sodium taurocholate and glucosyl-sphingosine, both of which regulate CBG enzymatic activity. Deficiencies in CBG have been implicated in Gaucher?s disease, a lysosomal storage disease that causes a build up of fatty material in the spleen, liver, lung and kidneys.
- 基因ID
- 57733
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