MIS18 Binding Protein 1 (MIS18BP1) 抗体 (AbBy Fluor® 594)
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- 抗原 See all MIS18 Binding Protein 1 (MIS18BP1) 抗体
- MIS18 Binding Protein 1 (MIS18BP1)
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- AbBy Fluor® 594
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应用范围
- Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human KNL2/C14orf106
- 亚型
- IgG
- Top Product
- Discover our top product MIS18BP1 Primary Antibody
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anti-MIS18 Binding Protein 1 (MIS18BP1) (AA 1-314) antibody
MIS18BP1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
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- 应用备注
- IF(IHC-P) 1:50-200
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- MIS18 Binding Protein 1 (MIS18BP1)
- 别名
- C14orf106 (MIS18BP1 产品)
- 别名
- C14orf106 antibody, HSA242977 antibody, KNL2 antibody, M18BP1 antibody, 6720403H11 antibody, C79407 antibody, Knl2 antibody, mKIAA1903 antibody, MIS18 binding protein 1 antibody, MIS18BP1 antibody, Mis18bp1 antibody
- 背景
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Synonyms: Chromosome 14 open reading frame 106, HsKNL-2, KIAA1903, Kinetochore-associated protein KNL-2 homolog, M18BP1, Mis18-binding protein 1, MIS18BP1, P243, Putative protein p243 which interacts with transcription factor Sp1, Uncharacterized potential DNA binding protein C14orf106, M18BP_HUMAN.
Background: C14orf106 is required for recruitment of CENPA to centromeres and normal chromosome segregation during mitosis. It interacts with SP1. There are two isoforms.Chromosome 14 contains about 700 genes and 106 million base pairs and makes up about 3.5 % of human cellular DNA. Chromosome 14 encodes the presinilin 1 (PSEN1) gene, which is one of the three key genes associated with the development of Alzheimer's disease. The SERPINA1 gene is located on chromosome 14 and when defective leads to the genetic disorder ?-antitrypsin deficiency. This disorder is characterized by severe lung complications and liver dysfunction. Notably, the immunoglobulin heavy chain locus is found on chromosome 14 and has been identified as a fusion with the chromosome 19 encoded protein BCL3 in the (14,19) translocations found in a variety of B cell malignancies. The C14orf106 gene product has been provisionally designated C14orf106 pending further characterization.
- 途径
- Chromatin Binding
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