POLR3C 抗体 (AA 50-80)
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- 抗原 See all POLR3C 抗体
- POLR3C (Polymerase (RNA) III (DNA Directed) Polypeptide C (62kD) (POLR3C))
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抗原表位
- AA 50-80
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This POLR3C antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 交叉反应
- 人
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human POLR3C
- 亚型
- IgG
- Top Product
- Discover our top product POLR3C Primary Antibody
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anti-Polymerase (RNA) III (DNA Directed) Polypeptide C (62kD) (POLR3C) antibody
POLR3C 适用: 人 WB, IF, IHC (p), IHC 宿主: 小鼠 Monoclonal 2H1 unconjugated
anti-Polymerase (RNA) III (DNA Directed) Polypeptide C (62kD) (POLR3C) (AA 1-534) antibodyPOLR3C 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Polymerase (RNA) III (DNA Directed) Polypeptide C (62kD) (POLR3C) (AA 1-534) antibodyPOLR3C 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Polymerase (RNA) III (DNA Directed) Polypeptide C (62kD) (POLR3C) (Internal Region) antibodyPOLR3C 适用: 人 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Polymerase (RNA) III (DNA Directed) Polypeptide C (62kD) (POLR3C) (AA 1-534) antibodyPOLR3C 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Polymerase (RNA) III (DNA Directed) Polypeptide C (62kD) (POLR3C) antibodyPOLR3C 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Polymerase (RNA) III (DNA Directed) Polypeptide C (62kD) (POLR3C) (C-Term) antibodyPOLR3C 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, Hamster, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Polymerase (RNA) III (DNA Directed) Polypeptide C (62kD) (POLR3C) (AA 1-270) antibodyPOLR3C 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Polymerase (RNA) III (DNA Directed) Polypeptide C (62kD) (POLR3C) (AA 202-230) antibodyPOLR3C 适用: 人 WB 宿主: 兔 Polyclonal RB36947 unconjugated
anti-Polymerase (RNA) III (DNA Directed) Polypeptide C (62kD) (POLR3C) (Middle Region) antibodyPOLR3C 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, Saccharomyces cerevisiae WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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- 抗原
- POLR3C (Polymerase (RNA) III (DNA Directed) Polypeptide C (62kD) (POLR3C))
- 别名
- POLR3C (POLR3C 产品)
- 别名
- rpc3 antibody, rpc62 antibody, 4933407E01Rik antibody, RPC3 antibody, RPC62 antibody, zgc:56348 antibody, polymerase (RNA) III (DNA directed) polypeptide C (62kD) S homeolog antibody, RNA polymerase III subunit C antibody, polymerase (RNA) III (DNA directed) polypeptide C (62kD) antibody, polymerase (RNA) III (DNA directed) polypeptide C antibody, polr3c.S antibody, POLR3C antibody, polr3c antibody, Polr3c antibody
- 背景
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Synonyms: RPC3, RPC62, DNA-directed RNA polymerase III subunit RPC3, RNA polymerase III subunit C3, DNA-directed RNA polymerase III subunit C, RNA polymerase III 62 kDa subunit, POLR3C
Background: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific core component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. May direct with other members of the subcomplex RNA Pol III binding to the TFIIIB-DNA complex via the interactions between TFIIIB and POLR3F. May be involved either in the recruitment and stabilization of the subcomplex within RNA polymerase III, or in stimulating catalytic functions of other subunits during initiation. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts, such as Epstein-Barr virus-encoded RNAs (EBERs) induce type I interferon and NF- Kappa-B through the RIG-I pathway.
- 基因ID
- 10623
- UniProt
- Q9BUI4
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