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Shootin-1 (SHTN1) (AA 21-130) 抗体 (AbBy Fluor® 594)

SHTN1 适用: 人, 大鼠 WB, IF (cc), IF (p) 宿主: 兔 Polyclonal AbBy Fluor® 594
产品编号 ABIN2806359
发货至: 中国
  • 抗原 See all Shootin-1 (SHTN1) 抗体
    Shootin-1 (SHTN1)
    抗原表位
    • 14
    • 2
    • 1
    • 1
    AA 21-130
    适用
    • 24
    • 17
    • 3
    • 2
    • 1
    • 1
    • 1
    人, 大鼠
    宿主
    • 24
    克隆类型
    • 24
    多克隆
    标记
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AbBy Fluor® 594
    应用范围
    • 18
    • 12
    • 12
    • 3
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    交叉反应
    人, 大鼠
    预测反应
    Mouse,Cow,Pig,Horse
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human Shootin/KIAA1598
    亚型
    IgG
    Top Product
    Discover our top product SHTN1 Primary Antibody
  • 应用备注
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    Shootin-1 (SHTN1)
    别名
    Shootin/KIAA1598 (SHTN1 产品)
    别名
    Kiaa1598 antibody, Shootin1 antibody, mKIAA1598 antibody, shootin 1 antibody, SHTN1 antibody, Shtn1 antibody
    背景

    Synonyms: DKFZp686A0439, hypothetical protein FLJ11122, Kiaa1598, MGC40476, Putative uncharacterized protein KIAA1598, Shootin 1, Shootin-1, SHOT1_HUMAN.

    Background: Shootin1 is a 631 amino acid protein that belongs to the shootin family. The shootin1 protein contains three coiled-coil domains, a proline-rich region and interacts with RUFY3. Shootin1 is involved in the generation of internal asymmetric signals required for neuronal polarization. The shootin1 protein acts upstream of PI3K (phosphoinositide 3-kinase), by being required for spatially localized PI3K activity. By accumulating asymmetrically in a single neurite before polarization, shootin1 leads to axon induction for polarization, additionally the absence of shootin1 from the nascent axon's siblings by competition prevents the formation of surplus axons. Existing as seven alternatively spliced isoforms, the shootin1 gene is conserved in chimpanzee, dog, mouse, rat, chicken and zebrafish, and maps to human chromosome 10q25.3.

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