Prominin 2 抗体 (AA 301-400) (AbBy Fluor® 594)
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- 抗原 See all Prominin 2 (PROM2) 抗体
- Prominin 2 (PROM2)
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抗原表位
- AA 301-400
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Prominin 2 antibody is conjugated to AbBy Fluor® 594
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应用范围
- Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- 交叉反应
- 人
- 预测反应
- Mouse,Rat,Dog,Pig
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human Prominin 2
- 亚型
- IgG
- Top Product
- Discover our top product PROM2 Primary Antibody
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- 应用备注
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FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- Prominin 2 (PROM2)
- 别名
- Prominin 2 (PROM2 产品)
- 别名
- PROML2 antibody, Prom-rp antibody, Promrp antibody, Trprp antibody, AI507243 antibody, PROM2 antibody, prom3 antibody, proml3 antibody, fd36c02 antibody, fo25d03 antibody, wu:fd36c02 antibody, prom-2 antibody, prominin 2 antibody, prominin 2 L homeolog antibody, PROM2 antibody, Prom2 antibody, prom2 antibody, prom2.L antibody
- 背景
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Synonyms: PROML2, Prominin-2, PROM-2, Prominin-like protein 2, hPROML2, PROM2, UNQ2521/PRO6014
Background: Prominin 2 is a 112 kDa glycoporotein structurally related to Prominin 1 (CD133) although amino acid similarity is not more than 30 % , but their genomic organization is strikingly similar. Like Prominin 1, the prominin 2 exhibit similar membrane topology with 5 trans-membrane domains and two large glycosylated extracellular domains. Similar to Prominin1 localization, the Prominin 2 is also associated with membrane protrusions of the epithelial cells from adult kidney, and all along the digestive track and other epithelial tissues.Prominin 2 expression is down-regulated in aggressive prostate cancer cell lines and transient transfection of PROML2 expression vectors has been shown to induce apoptosis in cultured prostate cancer cells, suggesting a tumor suppressive role for Prominin 2. Prominin 2 expression is likely to be involved in growth suppression in the prostate, and down-regulation of Prominin 2 may disrupt normal prostatic homeostasis and lead to uncontrolled prostatic growth.
- 基因ID
- 150696
- UniProt
- Q8N271
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