PIRT 抗体 (AA 51-137) (AbBy Fluor® 594)
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- 抗原 See all PIRT 抗体
- PIRT (Phosphoinositide-Interacting Regulator of Transient Receptor Potential Channels (PIRT))
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抗原表位
- AA 51-137
- 适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PIRT antibody is conjugated to AbBy Fluor® 594
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应用范围
- Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- 预测反应
- Human,Mouse,Rat,Dog,Cow,Sheep,Horse,Rabbit
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human PIRT
- 亚型
- IgG
- Top Product
- Discover our top product PIRT Primary Antibody
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- 应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- PIRT (Phosphoinositide-Interacting Regulator of Transient Receptor Potential Channels (PIRT))
- 别名
- PIRT (PIRT 产品)
- 别名
- A530088H08Rik antibody, RGD1565284 antibody, phosphoinositide interacting regulator of transient receptor potential channels antibody, phosphoinositide-interacting regulator of transient receptor potential channels antibody, PIRT antibody, Pirt antibody
- 背景
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Synonyms: hCG_1776018, Phosphoinositide interacting regulator of transient receptor potential channels , Phosphoinositide-interacting protein, Pirt, PIRT_HUMAN.
Background: PIRT is a 137 amino acid multi-pass membrane protein. Highly conserved among vertebrates, PIRT consists of two transmembrane domains and one putative C-terminal phosphoinositide-binding domain. Although PIRT is expressed in peripheral nervous system, with highest levels in dorsal root ganglion and trigeminal neurons, and lowest levels in sympathetic and enteric neurons, it is not expressed in spinal cord. PIRT is a required component of the VR1 complex, which positively regulates VR1, a sensor of both noxious heat and capsaicin. Correspondingly, PIRT knockout results in impaired responses to noxious heat and capsaicin exposure, while VR1 remains unaltered. The gene that encodes PIRT maps to human chromosome 17p13.1.
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