MLLT11 抗体 (AA 41-90) (AbBy Fluor® 594)
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- 抗原 See all MLLT11 抗体
- MLLT11 (Myeloid/lymphoid Or Mixed-Lineage Leukemia (Trithorax Homolog), Translocated To, 11 (MLLT11))
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抗原表位
- AA 41-90
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This MLLT11 antibody is conjugated to AbBy Fluor® 594
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应用范围
- Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- 交叉反应
- 人
- 预测反应
- Mouse,Rat,Dog,Cow,Pig,Horse,Rabbit
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human MLLT11
- 亚型
- IgG
- Top Product
- Discover our top product MLLT11 Primary Antibody
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- 应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- MLLT11 (Myeloid/lymphoid Or Mixed-Lineage Leukemia (Trithorax Homolog), Translocated To, 11 (MLLT11))
- 别名
- MLLT11 (MLLT11 产品)
- 别名
- AF1Q antibody, RP11-316M1.10 antibody, AI839562 antibody, Af1q antibody, Zfp692 antibody, RGD1305525 antibody, fc23g02 antibody, si:ch211-210h11.4 antibody, wu:fc23g02 antibody, myeloid/lymphoid or mixed-lineage leukemia; translocated to, 11 antibody, MLLT11, transcription factor 7 cofactor antibody, MLLT11 antibody, Mllt11 antibody, mllt11 antibody
- 背景
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Synonyms: AF1Q, ALL1 fused gene from chromosome 1q, MLLT 11, MLLT-11, Myeloid/lymphoid or mixed lineage leukemia trithorax homolog, Drosophila translocated to 11, Protein AF1q, RP11 316M1.10.
Background: The gene encoding the Mixed-Lineage Leukemia (MLL) proteins is located on chromosome 11q23. Chromosomal translocations involving band 11q23 result in rogue activator proteins that are associated with approximately 10 % of patients with acute lymphoblastic leukemia (ALL) and 5 % of patients with acute myeloid leukemia (AML). Most patients affected are less than 1 year of age. MLLT11, also known as mixed-lineage leukemia translocated to 11 or AF1q, is a 90 amino acid MLL fusion partner. Based on the expression patterns of MLLT11, it is thought that MLLT11 plays a role in leukemogenesis and, specifically, the progression of acute monocytic leukemia (AML). Also, expressed in embryonic brain cortex, MLLT11 is upregulated during neuronal differentiation and is thought to play a role in the development of the central nervous system. Finally, MLLT11 has been shown to be differentially expressed in highly metastatic cells, in comparison with non-metastatic parent cells. Such findings suggest a role of MLLT11 in tumorigenesis.
- 基因ID
- 10962
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