LLGL1 + LLGL2 (pSer650), (pSer654) 抗体 (AbBy Fluor® 594)
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- 抗原
- LLGL1 + LLGL2
- 抗原表位
- pSer650, pSer654
- 适用
- 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- AbBy Fluor® 594
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应用范围
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- 交叉反应
- 大鼠
- 预测反应
- Human,Mouse,Dog,Cow,Pig,Horse,Chicken,Guinea Pig
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic phosphopeptide derived from mouse LLGL1 around the phosphorylation site of Ser650+Ser654
- 亚型
- IgG
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- 应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- LLGL1 + LLGL2
- 别名
- LLGL1 + LLGL2+
- 背景
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Synonyms: LLGL1 + LLGL2 phospho S650 + S654, LLGL1 + LLGL2 phospho Ser650 + Ser654, p-LLGL1 + p-LLGL2 S650 + S654, p-LLGL1/LLGL2 Ser650 + Ser654, p-LLGL1/LLGL2 S650 + S654, p-LLGL1/LLGL2 Ser650/654, DLG4, HGL, HUGL, HUGL1, lethal giant larvae homolog 1, lethal giant larvae homolog 2, Lethal2 giant larvae protein homolog 1, Lethal2 giant larvae protein homolog 2, LGL2, LLGL, L2GL1_HUMAN, L2GL2_HUMAN.
Background: LLGL1 is a protein that is similar to a tumor suppressor in Drosophila. The protein is part of a cytoskeletal network and is associated with nonmuscle myosin II heavy chain and a kinase that specifically phosphorylates this protein at serine residues. The gene for LLGL1 is located within the Smith-Magenis syndrome region on chromosome 17. LLGL2 is a protein similar to lethal giant larvae of Drosophila. In fly, the protein's ability to localize cell fate determinants is regulated by the atypical protein kinase C (aPKC). In human, this protein interacts with aPKC-containing complexes and is cortically localized in mitotic cells.
- 基因ID
- 3996
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