CILP 抗体 (AA 1051-1184) (AbBy Fluor® 594)
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- 抗原 See all CILP 抗体
- CILP (Cartilage Intermediate Layer Protein, Nucleotide Pyrophosphohydrolase (CILP))
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抗原表位
- AA 1051-1184
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适用
- 人, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CILP antibody is conjugated to AbBy Fluor® 594
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应用范围
- Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- 特异性
- The immunogen falls within the Cartilage intermediate layer protein 1 C2 region.
- 交叉反应
- 人, 大鼠
- 预测反应
- Mouse,Cow,Sheep,Horse
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human CILP
- 亚型
- IgG
- Top Product
- Discover our top product CILP Primary Antibody
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- 应用备注
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FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- CILP (Cartilage Intermediate Layer Protein, Nucleotide Pyrophosphohydrolase (CILP))
- 别名
- CILP (CILP 产品)
- 别名
- CILP-1 antibody, HsT18872 antibody, 9830114D16 antibody, C130036G17Rik antibody, NTPPH antibody, CILP antibody, im:7137994 antibody, cartilage intermediate layer protein antibody, cartilage intermediate layer protein, nucleotide pyrophosphohydrolase antibody, cartilage intermediate layer protein 1 antibody, CILP antibody, Cilp antibody, cilp antibody, LOC100336614 antibody
- 背景
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Synonyms: CILP-1, HsT18872, Cartilage intermediate layer protein 1, Cartilage intermediate-layer protein, CILP, UNQ602/PRO1188
Background: Probably plays a role in cartilage scaffolding. May act by antagonizing TGF-beta1 (TGFB1) and IGF1 functions. Has the ability to suppress IGF1-induced proliferation and sulfated proteoglycan synthesis, and inhibits ligand-induced IGF1R autophosphorylation. May inhibit TGFB1-mediated induction of cartilage matrix genes via its interaction with TGFB1. Overexpression may lead to impair chondrocyte growth and matrix repair and indirectly promote inorganic pyrophosphate (PPi) supersaturation in aging and osteoarthritis cartilage.
- 基因ID
- 8483
- UniProt
- O75339
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