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FOLR2 抗体

FOLR2 适用: 人 WB, FACS, IP, ICC 宿主: 小鼠 Monoclonal EM-35 unconjugated
产品编号 ABIN2800693
发货至: 中国
  • 抗原 See all FOLR2 抗体
    FOLR2 (Folate Receptor 2 (Fetal) (FOLR2))
    适用
    • 51
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    宿主
    • 46
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    小鼠
    克隆类型
    • 45
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    单克隆
    标记
    • 27
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    This FOLR2 antibody is un-conjugated
    应用范围
    • 42
    • 29
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    Western Blotting (WB), Flow Cytometry (FACS), Immunoprecipitation (IP), Immunocytochemistry (ICC)
    特异性
    The mouse monoclonal antibody EM-35 recognizes an extracellular epitope on FOLR2, a 30-40 kDa cell surface protein serving as a receptor for folic acid.
    无交叉反应
    小鼠
    交叉反应 (详细)
    Human
    纯化方法
    Purified by protein-A affinity chromatography.
    纯度
    > 95 % (by SDS-PAGE)
    免疫原
    BW5147alpha,beta- cells
    克隆位点
    EM-35
    亚型
    IgG1
    Top Product
    Discover our top product FOLR2 Primary Antibody
  • 应用备注
    Western blotting: Non-reducing conditions.
    Flow cytometry: Recommended dilution: 1-4 μg/mL
    限制
    仅限研究用
  • 浓度
    1 mg/mL
    缓冲液
    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store at 2-8°C. Do not freeze.
  • 抗原
    FOLR2 (Folate Receptor 2 (Fetal) (FOLR2))
    别名
    FOLR2 (FOLR2 产品)
    别名
    FOLR2 antibody, BETA-HFR antibody, FBP antibody, FBP/PL-1 antibody, FR-BETA antibody, FR-P3 antibody, FBP2 antibody, Folbp-2 antibody, Folbp2 antibody, folate receptor 1 antibody, folate receptor beta antibody, folate receptor 2 (fetal) antibody, FOLR1 antibody, FOLR2 antibody, Folr2 antibody
    背景
    Folate receptor beta,FOLR2 (folate receptor beta) is a cell surface protein that was originally thought to be specific for placenta, but it can be also expressed in other tissues, including hematopoietic cells. Its expression is increased in malignant tissues. FOLR2 may play a role in the transport of methotrexate in synovial macrophages in rheumatoid arthritis patients. FOLR2 is a marker for macrophages generated in the presence of M-CSF (M2), including M2-like tumor-associated macrophages, which exert potent immunosuppressive functions within the tumor environment, but not GM-CSF (M1), and whose expression correlates with increased folate uptake ability.,Folate receptor beta, FBP, FR-P3, FR-BETA, BETA-HFR, FBP/PL-1
    基因ID
    2350
    UniProt
    P14207
    途径
    Dicarboxylic Acid Transport
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