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FOLR2 抗体

This anti-FOLR2 antibody is a 小鼠 单克隆 antibody detecting FOLR2 in WB, FACS, IP 和 ICC. Suitable for 人.
产品编号 ABIN2800693
发货至: 中国

Quick Overview for FOLR2 抗体 (ABIN2800693)

抗原

See all FOLR2 抗体
FOLR2 (Folate Receptor 2 (Fetal) (FOLR2))

适用

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宿主

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小鼠

克隆类型

  • 36
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单克隆

标记

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This FOLR2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Flow Cytometry (FACS), Immunoprecipitation (IP), Immunocytochemistry (ICC)

克隆位点

EM-35
  • 原理

    Anti-FOLR2 Purified

    特异性

    The mouse monoclonal antibody EM-35 recognizes an extracellular epitope on FOLR2, a 30-40 kDa cell surface protein serving as a receptor for folic acid.

    无交叉反应

    小鼠

    交叉反应 (详细)

    Human

    纯化方法

    Purified by protein-A affinity chromatography.

    纯度

    > 95 % (by SDS-PAGE)

    免疫原

    BW5147alpha,beta- cells

    亚型

    IgG1
  • 应用备注

    Western blotting: Non-reducing conditions.
    Flow cytometry: Recommended dilution: 1-4 μg/mL

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store at 2-8°C. Do not freeze.
  • 抗原

    FOLR2 (Folate Receptor 2 (Fetal) (FOLR2))

    别名

    FOLR2

    背景

    Folate receptor beta,FOLR2 (folate receptor beta) is a cell surface protein that was originally thought to be specific for placenta, but it can be also expressed in other tissues, including hematopoietic cells. Its expression is increased in malignant tissues. FOLR2 may play a role in the transport of methotrexate in synovial macrophages in rheumatoid arthritis patients. FOLR2 is a marker for macrophages generated in the presence of M-CSF (M2), including M2-like tumor-associated macrophages, which exert potent immunosuppressive functions within the tumor environment, but not GM-CSF (M1), and whose expression correlates with increased folate uptake ability.,Folate receptor beta, FBP, FR-P3, FR-BETA, BETA-HFR, FBP/PL-1

    基因ID

    2350

    UniProt

    P14207

    途径

    Dicarboxylic Acid Transport
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