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HAT1 抗体 (C-Term)

HAT1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2797110
发货至: 中国
  • 抗原 See all HAT1 抗体
    HAT1 (Histone Aminotransferase 1 (HAT1))
    抗原表位
    • 2
    • 1
    • 1
    • 1
    AA 389-419, C-Term
    适用
    宿主
    • 4
    克隆类型
    • 4
    多克隆
    标记
    • 4
    This HAT1 antibody is un-conjugated
    应用范围
    Western Blotting (WB)
    原理
    Rabbit Anti-Human KAT1 (HAT1) (C-term) Antibody
    免疫原
    This KAT1 (HAT1) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 389-419 amino acids from the C-terminal region of human KAT1 (HAT1).
    亚型
    Ig Fraction
    Top Product
    Discover our top product HAT1 Primary Antibody
  • 应用备注
    Western Blot
    Recommended Dilutions
    WB: 1:1000Western blot analysis of hHAT1-E404 was detected using the purified Pab.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    2.0 mg/mL
    储存条件
    4 °C,-20 °C
    储存方法
    2-8°C (short-term), -20°C (long-term)
  • 抗原
    HAT1 (Histone Aminotransferase 1 (HAT1))
    别名
    KAT1 (HAT1 产品)
    别名
    GTK antibody, KAT1 antibody, KATI antibody, kynurenine aminotransferase 1 antibody, KYAT1 antibody
    背景

    Target Description: Histone acetylation, particularly of histone H4, has been proposed to play an important role in replication-dependent nucleosome assembly. The HAT1 protein contains D, A, and B motifs, which are present in many N-acetyltransferases, including those that acetylate substrates other than histones. The HAT1 holoenzyme consists of 2 subunits: the catalytic 46-kD HAT1 and the accessory p46. The p46 subunit stimulated the activity of HAT1 and bound to core histones. The HAT1 holoenzyme acetylated newly synthesized but not nucleosomal histone H4 at lys5 and lys12, and, to a lesser extent, histone H2A at lys5. HAT1 and p46 polypeptides are located in the nucleus of S-phase cells. HAT1 may play a role in telomeric silencing.

    Gene Symbol: HAT1

    分子量
    49513 Da
    基因ID
    8520
    UniProt
    O14929
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