KDELR1 抗体 (C-Term)
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- 抗原 See all KDELR1 抗体
- KDELR1 (KDEL (Lys-Asp-Glu-Leu) Endoplasmic Reticulum Protein Retention Receptor 1 (KDELR1))
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抗原表位
- AA 185-211, C-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This KDELR1 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 原理
- Rabbit Anti-Human KDELR1 (C-term) Antibody
- 免疫原
- This KDELR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 185-211 amino acids from the C-terminal region of human KDELR1.
- 亚型
- Ig Fraction
- Top Product
- Discover our top product KDELR1 Primary Antibody
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- 应用备注
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Western Blot
Recommended Dilutions
WB: 1:1000KDELR1 Antibody (C-term) . - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.470 mg/mL
- 储存条件
- 4 °C,-20 °C
- 储存方法
- 2-8°C (short-term), -20°C (long-term)
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- 抗原
- KDELR1 (KDEL (Lys-Asp-Glu-Leu) Endoplasmic Reticulum Protein Retention Receptor 1 (KDELR1))
- 别名
- KDELR1 (KDELR1 产品)
- 别名
- ERD2 antibody, ERD2.1 antibody, HDEL antibody, PM23 antibody, 8030486F04Rik antibody, AW215843 antibody, Erd2.1 antibody, KDEL endoplasmic reticulum protein retention receptor 1 antibody, KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 antibody, KDELR1 antibody, Kdelr1 antibody
- 背景
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Target Description: Retention of resident soluble proteins in the lumen of the endoplasmic reticulum (ER) is achieved in both yeast and animal cells by their continual retrieval from the cis-Golgi, or a pre-Golgi compartment. Sorting of these proteins is dependent on a C-terminal tetrapeptide signal, usually lys-asp-glu-leu (KDEL) in animal cells, and his-asp-glu-leu (HDEL) in S. cerevisiae. This process is mediated by a receptor that recognizes, and binds the tetrapeptide-containing protein, and returns it to the ER. In yeast, the sorting receptor encoded by a single gene, ERD2, which is a seven-transmembrane protein. Unlike yeast, several human homologs of the ERD2 gene, constituting the KDEL receptor gene family, have been described. The protein encoded by this gene was the first member of the family to be identified, and it encodes a protein structurally and functionally similar to the yeast ERD2 gene product.
Gene Symbol: KDELR1
- 分子量
- 24542 Da
- 基因ID
- 10945
- UniProt
- P24390
- 途径
- Maintenance of Protein Location
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