(6 references)-
- 抗原 See all Nucleobindin 1 (NUCB1) 抗体
- Nucleobindin 1 (NUCB1)
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抗原表位
- C-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Nucleobindin 1 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- PAAHPEGQLK FHPDTDDVPV PAPAGDQKEV DTSEKKLLER LPEVEVPQHL
- 交叉反应
- 人
- 预测反应
- Human: 100%
- 产品特性
- This is a rabbit polyclonal antibody against NUCB1. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human NUCB1
- Top Product
- Discover our top product NUCB1 Primary Antibody
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anti-Nucleobindin 1 (NUCB1) (AA 28-461) antibody
NUCB1 适用: 人 WB, IF, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 1H8-2C11 unconjugated
anti-Nucleobindin 1 (NUCB1) (AA 302-461) antibodyNUCB1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Nucleobindin 1 (NUCB1) (AA 1-461) antibodyNUCB1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Nucleobindin 1 (NUCB1) (C-Term) antibodyNUCB1 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Nucleobindin 1 (NUCB1) (AA 26-413) antibodyNUCB1 适用: 小鼠 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Nucleobindin 1 (NUCB1) (C-Term) antibodyNUCB1 适用: 小鼠, 大鼠, 犬 IHC 宿主: 兔 Polyclonal unconjugated
anti-Nucleobindin 1 (NUCB1) (AA 1-461) antibodyNUCB1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Nucleobindin 1 (NUCB1) (C-Term) antibodyNUCB1 适用: 大鼠, 犬 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Nucleobindin 1 (NUCB1) (C-Term) antibodyNUCB1 适用: 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Nucleobindin 1 (NUCB1) (C-Term) antibodyNUCB1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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WB Suggested Anti-NUCB1 Antibody Titration: 0.2-1 µg/mL
ELISA Titer: 1:1562500
Positive Control: HepG2 cell lysate.
Optimal working dilutions should be determined experimentally by the investigator. - 说明
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Antigen size: 461 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "Nucleobindin 1 binds to multiple types of pre-fibrillar amyloid and inhibits fibrillization." in: Scientific reports, Vol. 7, pp. 42880, (2017) (PubMed).
: "Topology and membrane anchoring of the lysosomal storage disease-related protein CLN5." in: Human mutation, Vol. 34, Issue 12, pp. 1688-97, (2013) (PubMed).
: "Calnuc plays a role in dynamic distribution of Galphai but not Gbeta subunits and modulates ACTH secretion in AtT-20 neuroendocrine secretory cells." in: Molecular neurodegeneration, Vol. 4, pp. 15, (2009) (PubMed).
: "Modulation of nucleobindin-1 and nucleobindin-2 by caspases." in: FEBS letters, Vol. 582, Issue 2, pp. 286-90, (2008) (PubMed).
: "Serine 129 phosphorylation of alpha-synuclein induces unfolded protein response-mediated cell death." in: The Journal of biological chemistry, Vol. 283, Issue 34, pp. 23179-88, (2008) (PubMed).
: "Calnuc binds to Alzheimer's beta-amyloid precursor protein and affects its biogenesis." in: Journal of neurochemistry, Vol. 100, Issue 6, pp. 1505-14, (2007) (PubMed).
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: "Nucleobindin 1 binds to multiple types of pre-fibrillar amyloid and inhibits fibrillization." in: Scientific reports, Vol. 7, pp. 42880, (2017) (PubMed).
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- 抗原
- Nucleobindin 1 (NUCB1)
- 别名
- Nucleobindin-1 (NUCB1 产品)
- 背景
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Nucleobindin, also known as calnuc, participates in Ca2+ storage in the Golgi, as well as in other biological processes that involve DNA-binding and protein-protein interactions.
Alias Symbols: NUC, CALNUC
Protein Interaction Partner: REL, UBC, MDM2, CTPS2, RAD23B, PRKDC, METTL1, GTF2I, CBS, XPNPEP1, WARS, PTGS2, XPO1, SET, RBL1, MYC, HIVEP1, GNAS, GNAI3, GNAI1, KLC4, PTGS1, NDN, GNAI2, GNAO1, GNAZ,
Protein Size: 461 - 分子量
- 54 kDa
- 基因ID
- 4924
- NCBI登录号
- NM_006184, NP_006175
- UniProt
- Q02818
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