CDK7 抗体 (Middle Region)
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- 抗原 See all CDK7 抗体
- CDK7 (Cyclin-Dependent Kinase 7 (CDK7))
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抗原表位
- Middle Region
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适用
- 人, 大鼠, Cow, Pig, 马, 犬, 豚鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CDK7 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- TQALKMKYFS NRPGPTPGCQ LPRPNCPVET LKEQSNPALA IKRKRTEALE
- 交叉反应
- 牛, 犬, 人, 猪, 大鼠
- 预测反应
- Cow: 80%, Dog: 86%, Guinea Pig: 78%, Horse: 86%, Human: 100%, Pig: 86%, Rat: 86%
- 产品特性
- This is a rabbit polyclonal antibody against CDK7. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human CDK7
- Top Product
- Discover our top product CDK7 Primary Antibody
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- 应用备注
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WB Suggested Anti-CDK7 Antibody Titration: 0.2-1 µg/mL
ELISA Titer: 1:12500
Positive Control: THP-1 cell lysate.
Optimal working dilutions should be determined experimentally by the investigator. - 说明
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Antigen size: 346 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- CDK7 (Cyclin-Dependent Kinase 7 (CDK7))
- 别名
- CDK7 (CDK7 产品)
- 背景
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CDK7 is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This protein forms a trimeric complex with cyclin H and MAT1, which functions as a Cdk-activating kinase (CAK). It is an essential component of the transcription factor TFIIH, that is involved in transcription initiation and DNA repair. This protein is thought to serve as a direct link between the regulation of transcription and the cell cycle.The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This protein forms a trimeric complex with cyclin H and MAT1, which functions as a Cdk-activating kinase (CAK). It is an essential component of the transcription factor TFIIH, that is involved in transcription initiation and DNA repair. This protein is thought to serve as a direct link between the regulation of transcription and the cell cycle. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: CAK1, CDKN7, MO15, STK1, p39MO15, HCAK
Protein Interaction Partner: UBC, RPA3, RPA2, RPA1, GTF2H4, GTF2H3, GTF2H2, GTF2H1, ERCC5, ERCC3, ERCC2, CDK7, CCNH, ATP2B4, A2M, GTF2H5, SRPK2, SRPK1, MNAT1, TP53, CDK2, CTD, MBP, CDK1, CCNB1, CCNA2, Dlg4, UVSSA, HSP90AA1, HSD17B4, HLA-DQA1, SUPT5H, POLR2A, GTF2E2, GTF2E1, CDK9, APP
Protein Size: 346 - 分子量
- 39 kDa
- 基因ID
- 1022
- NCBI登录号
- NM_001799, NP_001790
- UniProt
- P50613
- 途径
- Cell Division Cycle, DNA Damage Repair, Intracellular Steroid Hormone Receptor Signaling Pathway, Mitotic G1-G1/S Phases, M Phase
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