GTF2B 抗体 (N-Term)
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- 抗原 See all GTF2B 抗体
- GTF2B (General Transcription Factor IIB (GTF2B))
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抗原表位
- N-Term
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适用
- 人, 小鼠, 犬, 斑马鱼, 马, 豚鼠, 兔
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This GTF2B antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 序列
- NLPRNIVDRT NNLFKQVYEQ KSLKGRANDA IASACLYIAC RQEGVPRTFK
- 交叉反应
- 牛, 犬, 人, 小鼠, 大鼠
- 预测反应
- Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Zebrafish: 92%
- 产品特性
- This is a rabbit polyclonal antibody against GTF2B. It was validated on Western Blot and immunohistochemistry.
- 纯化方法
- Protein A purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human GTF2B
- Top Product
- Discover our top product GTF2B Primary Antibody
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- 应用备注
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WB Suggested Anti-GTF2B Antibody Titration: 4.0 µg/mL
Positive Control: HepG2 cell lysate.
Optimal working dilutions should be determined experimentally by the investigator. - 说明
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Antigen size: 316 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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A nonconserved surface of the TFIIB zinc ribbon domain plays a direct role in RNA polymerase II recruitment." in: Molecular and cellular biology, Vol. 24, Issue 7, pp. 2863-74, (2004) (PubMed).
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A nonconserved surface of the TFIIB zinc ribbon domain plays a direct role in RNA polymerase II recruitment." in: Molecular and cellular biology, Vol. 24, Issue 7, pp. 2863-74, (2004) (PubMed).
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- 抗原
- GTF2B (General Transcription Factor IIB (GTF2B))
- 别名
- GTF2B (GTF2B 产品)
- 别名
- CG5193 antibody, Dmel\\CG5193 antibody, TFIIB antibody, Tfiib antibody, TfllB antibody, dTFIIB antibody, dTfIIB antibody, dmTFIIB antibody, gtf2b antibody, tf2b antibody, tfiib antibody, XLTFIIB antibody, TF2B antibody, wu:fc44c11 antibody, zgc:66258 antibody, Transcription factor IIB antibody, transcription initiation factor iib antibody, transcription initiation factor IIB antibody, transcription initiation factor IIB 2 antibody, Transcription initiation factor IIB antibody, general transcription factor 2B S homeolog antibody, general transcription factor 2B L homeolog antibody, general transcription factor IIB antibody, TfIIB antibody, CNF01950 antibody, tfb antibody, CC1G_14689 antibody, HacjB3_18813 antibody, HALXA_RS07110 antibody, HALXA_RS16310 antibody, tf2b antibody, LOC100283348 antibody, gtf2b.S antibody, gtf2b.L antibody, GTF2B antibody, gtf2b antibody, Gtf2b antibody
- 背景
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GTF2B is the general transcription factor IIB, one of the ubiquitous factors required for transcription initiation by RNA polymerase II. The protein localizes to the nucleus where it forms a complex (the DAB complex) with transcription factors IID and IIA. Transcription factor IIB serves as a bridge between IID, the factor which initially recognizes the promoter sequence, and RNA polymerase II.
Alias Symbols: TF2B, TFIIB
Protein Interaction Partner: DRAP1, TNIP1, UBC, FBXO25, HNF4A, TCEA1, GTF2F2, GTF2F1, DEPDC7, SLC22A2, RELA, POLR2C, JAK3, HMGCL, SMURF1, THRA, TBP, POLR2E, SRA1, LSM4, LSM5, CIITA, NXF1, POU3F2, EP300, PSMA3, POLR2J, ESR1, UL48, NR1D2, NCOR1, TAF9, REST, tat, SAP25, MKX, CTDP1, POLR
Protein Size: 316 - 分子量
- 35 kDa
- 基因ID
- 2959
- NCBI登录号
- NM_001514, NP_001505
- UniProt
- Q00403
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