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E2F5 抗体 (N-Term)

E2F5 适用: 人, 小鼠, 大鼠, 犬, 豚鼠, 斑马鱼, 兔 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2792655
发货至: 中国
  • 抗原 See all E2F5 抗体
    E2F5
    抗原表位
    • 8
    • 7
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 39
    • 13
    • 7
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠, 犬, 豚鼠, 斑马鱼, 兔
    宿主
    • 36
    • 3
    克隆类型
    • 36
    • 3
    多克隆
    标记
    • 17
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This E2F5 antibody is un-conjugated
    应用范围
    • 28
    • 22
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    序列
    KAEIEDLELK ERELDQQKLL LQQSIKNVMD DSINNRFSYV THEDICNCFN
    交叉反应
    小鸡, 人, 小鼠, 大鼠
    预测反应
    Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 84%
    产品特性
    This is a rabbit polyclonal antibody against E2F5. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the N terminal region of human E2F5
    Top Product
    Discover our top product E2F5 Primary Antibody
  • 应用备注
    WB Suggested Anti-E2F5 Antibody Titration: 0.2-1 µg/mL
    Positive Control: Jurkat cell lysate.
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 346 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    E2F5
    别名
    E2F5 (E2F5 产品)
    别名
    AU024671 antibody, E2F-5 antibody, E2f-5 antibody, E2F4 antibody, cb735 antibody, zgc:111879 antibody, E2F transcription factor 5 antibody, E2f5 antibody, e2f5 antibody, E2F5 antibody
    背景
    E2F5 is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein is differentially phosphorylated and is expressed in a wide variety of human tissues. It is more homologous to E2F4, a family member, than to other members. Both this protein and E2F4 interact with tumor suppressor proteins p130 and p107, but not with pRB.
    Alias Symbols: E2F-5
    Protein Interaction Partner: RBL2, UBC, KMT2D, BRCC3, SMAD3, EP300, XPO1, CREBBP, TFDP1, RBL1, BIRC5, MYC, MT1G,
    Protein Size: 346
    分子量
    38 kDa
    基因ID
    1875
    NCBI登录号
    NM_001951, NP_001942
    UniProt
    Q15329
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