DP1 抗体 (Middle Region)
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- 抗原 See all DP1 (TFDP1) 抗体
- DP1 (TFDP1) (Transcription Factor Dp-1 (TFDP1))
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抗原表位
- Middle Region
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适用
- 人, 小鼠, Cow, 斑马鱼
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This DP1 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- FSASDLTNGA DGMLATSSNG SQYSGSRVET PVSYVGEDDE EDDDFNENDE
- 交叉反应
- 牛, 人, 小鼠, 大鼠
- 预测反应
- Cow: 92%, Human: 100%, Mouse: 100%, Zebrafish: 84%
- 产品特性
- This is a rabbit polyclonal antibody against TFDP1. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human TFDP1
- Top Product
- Discover our top product TFDP1 Primary Antibody
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- 应用备注
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WB Suggested Anti-TFDP1 Antibody Titration: 0.2-1 µg/mL
ELISA Titer: 1:62500
Positive Control: COLO205 cell lysate.
Optimal working dilutions should be determined experimentally by the investigator. - 说明
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Antigen size: 410 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- DP1 (TFDP1) (Transcription Factor Dp-1 (TFDP1))
- 别名
- TFDP1 (TFDP1 产品)
- 背景
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The E2F transcription factor family regulates the expression of various cellular promoters, particularly those involved in the cell cycle. E2F factors bind to DNA as homodimers or heterodimers in association with dimerization partner DP1. TFDP1 may be the first example of a family of related transcription factors and may have a role in progression of some hepatocellular carcinomas by promoting growth of the tumor cells. The E2F transcription factor family (see MIM 189971) regulates the expression of various cellular promoters, particularly those involved in the cell cycle. E2F factors bind to DNA as homodimers or heterodimers in association with dimerization partner DP1. TFDP1 may be the first example of a family of related transcription factors, see TFDP2 (MIM 602160).[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: DP1, DRTF1, Dp-1
Protein Interaction Partner: UBC, E2F6, E2F4, SIAH1, E2F3, E2F2, E2F1, CDK6, PRPF31, CDK2, CDK1, SOCS3, RB1, PCGF6, RYBP, YAF2, RNF2, ELAVL1, LIN9, LIN54, LIN37, RBL2, SERTAD2, NPDC1, E2F5, TP53, RBL1, CDK3, TP53BP1,
Protein Size: 410 - 分子量
- 45 kDa
- 基因ID
- 7027
- NCBI登录号
- NM_007111, NP_009042
- UniProt
- Q14186
- 途径
- Cell Division Cycle, Mitotic G1-G1/S Phases
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