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NFKBIL2 抗体 (Middle Region)

NFKBIL2 适用: 人, 小鼠, 大鼠, 犬 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2792627
发货至: 中国
  • 抗原 See all NFKBIL2 抗体
    NFKBIL2 (Tonsoku-Like, DNA Repair Protein (NFKBIL2))
    抗原表位
    • 14
    • 10
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    适用
    人, 小鼠, 大鼠, 犬
    宿主
    • 37
    • 5
    克隆类型
    • 40
    • 2
    多克隆
    标记
    • 22
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This NFKBIL2 antibody is un-conjugated
    应用范围
    • 28
    • 21
    • 4
    • 1
    Western Blotting (WB)
    序列
    RAIIHVSLAT TLGDMKDHHG AVRHYEEELR LRSGNVLEEA KTWLNIALSR
    交叉反应
    犬, 人, 小鼠, 大鼠
    预测反应
    Dog: 84%, Human: 100%, Mouse: 83%, Rat: 83%
    产品特性
    This is a rabbit polyclonal antibody against NFKBIL2. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the middle region of human NFKBIL2
    Top Product
    Discover our top product NFKBIL2 Primary Antibody
  • 应用备注
    WB Suggested Anti-NFKBIL2 Antibody Titration: 0.2-1 µg/mL
    ELISA Titer: 1:62500
    Positive Control: 293T cell lysate.
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 1219 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." in: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).

  • 抗原
    NFKBIL2 (Tonsoku-Like, DNA Repair Protein (NFKBIL2))
    别名
    NFKBIL2 / IKBR (NFKBIL2 产品)
    别名
    IKBR antibody, NFKBIL2 antibody, 2810439M11Rik antibody, Nfkbil2 antibody, im:7145273 antibody, nfkbil2 antibody, tonsl antibody, tonsoku like, DNA repair protein antibody, tonsoku-like, DNA repair protein antibody, TONSL antibody, Tonsl antibody, tonsl antibody
    背景
    NFKBIL2 is thought to be a negative regulator of NF-kappa-B mediated transcription. It may bind NF-kappa-B complexes and trap them in the cytoplasm, preventing them from entering the nucleus and interacting with the DNA. Phosphorylation of this protein targets it for degradation by the ubiquitination pathway, which frees the NF-kappa-B complexes to enter the nucleus.The protein encoded by this gene is thought to be a negative regulator of NF-kappa-B mediated transcription. The encoded protein may bind NF-kappa-B complexes and trap them in the cytoplasm, preventing them from entering the nucleus and interacting with the DNA. Phosphorylation of this protein targets it for degradation by the ubiquitination pathway, which frees the NF-kappa-B complexes to enter the nucleus.
    Alias Symbols: FLJ40087, IKBR, NFKBIL2
    Protein Interaction Partner: HIST3H3, MCM6, MCM2, MMS22L, ASF1B, ASF1A, UBC, MYC, MAU2, SLC25A5, SUPT16H, SUGT1, AIFM1, HIST1H2BL, XRCC5, SSRP1, SLC25A3, TONSL, MCM4, HIST1H2AE, HIST1H1B, HIST1H1C, XRCC6, GSK3B, MCM7, MCM5, MCM3, EWSR1,
    Protein Size: 1219
    分子量
    133 kDa
    基因ID
    4796
    NCBI登录号
    NM_013432, NP_038460
    UniProt
    Q96HA7
    途径
    Maintenance of Protein Location
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