NFX1 抗体 (Middle Region)
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- 抗原 See all NFX1 抗体
- NFX1 (Nuclear Transcription Factor, X-Box Binding 1 (NFX1))
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抗原表位
- Middle Region
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适用
- 人, 小鼠, 大鼠, 兔, 犬, Cow
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This NFX1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 序列
- TLTGVLEREM QARPPPPIPH HRHQSDKNPG SSNLQKITKE PIIDYFDVQD
- 交叉反应
- 牛, 犬, 人, 小鼠, 大鼠
- 预测反应
- Cow: 85%, Dog: 85%, Human: 100%, Mouse: 76%, Rabbit: 85%, Rat: 85%
- 产品特性
- This is a rabbit polyclonal antibody against NFX1. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human NFX1
- Top Product
- Discover our top product NFX1 Primary Antibody
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anti-Nuclear Transcription Factor, X-Box Binding 1 (NFX1) (AA 981-1080) antibody
NFX1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1D12 unconjugated
anti-Nuclear Transcription Factor, X-Box Binding 1 (NFX1) (C-Term) antibodyNFX1 适用: 人, 小鼠, 大鼠, 兔, 犬, Cow, 猴 WB, IHC (p), IHC 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Transcription Factor, X-Box Binding 1 (NFX1) (N-Term) antibodyNFX1 适用: 人, 猴 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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WB Suggested Anti-NFX1 Antibody Titration: 0.2-1 µg/mL
ELISA Titer: 1:312500
Positive Control: HepG2 cell lysate.
Optimal working dilutions should be determined experimentally by the investigator. - 说明
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Antigen size: 1120 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- NFX1 (Nuclear Transcription Factor, X-Box Binding 1 (NFX1))
- 别名
- NFX1 (NFX1 产品)
- 别名
- NFX1 antibody, NFX2 antibody, 1300017N15Rik antibody, 3000003M19Rik antibody, NFX.1 antibody, TEG-42 antibody, Tex42 antibody, nuclear transcription factor, X-box binding 1 antibody, nuclear transcription factor, x-box binding 1 antibody, NFX1 antibody, CpipJ_CPIJ011986 antibody, nfx1 antibody, Nfx1 antibody
- 背景
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MHC class II gene expression is controlled primarily at the transcriptional level by transcription factors that bind to the X and Y boxes, two highly conserved elements in the proximal promoter of MHC class II genes. NFX1 is a transcriptional repressor capable of binding to the conserved X box motif of HLA-DRA and other MHC class II genes in vitro. The protein may play a role in regulating the duration of an inflammatory response by limiting the period in which class II MHC molecules are induced by IFN-gamma.MHC class II gene expression is controlled primarily at the transcriptional level by transcription factors that bind to the X and Y boxes, two highly conserved elements in the proximal promoter of MHC class II genes. The protein encoded by this gene is a transcriptional repressor capable of binding to the conserved X box motif of HLA-DRA and other MHC class II genes in vitro. The protein may play a role in regulating the duration of an inflammatory response by limiting the period in which class II MHC molecules are induced by IFN-gamma. Three alternative splice variants, each of which encodes a different isoform, have been identified.
Alias Symbols: DKFZp779G2416, MGC20369, NFX2
Protein Interaction Partner: UBC, BMI1, HECW2, SRSF4, SRSF3, RPS19, RPS3A, RPL22, RPL17, RPL13, RPL7A, RPL6, RPL3, PABPC3, YBX1, NCL, HNRNPM, HSPA1A, HNRNPU, HNRNPH1, HNRNPA2B1, HIST1H2AE, EEF1A2, DMD, DDX5, FAM208B, PABPC1, RPL13A, LARP1, APC2, MATR3, HIST1H4E, USP9X, SIN3A, MAML3,
Protein Size: 1120 - 分子量
- 124 kDa
- 基因ID
- 4799
- NCBI登录号
- NM_002504, NP_002495
- UniProt
- Q12986
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