DEK 抗体 (Middle Region)
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- 抗原 See all DEK 抗体
- DEK (DEK Oncogene (DEK))
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抗原表位
- Middle Region
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适用
- 人, 小鼠, 大鼠, Cow, 兔, 豚鼠, 马, Pig
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This DEK antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- ELKETIKKLL ASANLEEVTM KQICKKVYEN YPTYDLTERK DFIKTTVKEL
- 交叉反应
- 牛, 小鸡, 人, 小鼠, 大鼠
- 预测反应
- Cow: 85%, Guinea Pig: 85%, Horse: 85%, Human: 100%, Mouse: 85%, Pig: 78%, Rabbit: 85%, Rat: 85%
- 产品特性
- This is a rabbit polyclonal antibody against DEK. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human DEK
- Top Product
- Discover our top product DEK Primary Antibody
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- 应用备注
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WB Suggested Anti-DEK Antibody Titration: 0.2-1 µg/mL
ELISA Titer: 1:1562500
Positive Control: MCF7 cell lysate.
Optimal working dilutions should be determined experimentally by the investigator. - 说明
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Antigen size: 375 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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Galactose-poly(ethylene glycol)-polyethylenimine for improved lung gene transfer." in: Biochemical and biophysical research communications, Vol. 375, Issue 3, pp. 378-83, (2008) (PubMed).
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Galactose-poly(ethylene glycol)-polyethylenimine for improved lung gene transfer." in: Biochemical and biophysical research communications, Vol. 375, Issue 3, pp. 378-83, (2008) (PubMed).
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- 抗原
- DEK (DEK Oncogene (DEK))
- 别名
- DEK (DEK 产品)
- 别名
- D6S231E antibody, DEK antibody, 1810019E15Rik antibody, D13H6S231E antibody, DEK proto-oncogene antibody, DEK proto-oncogene L homeolog antibody, DEK oncogene (DNA binding) antibody, DEK oncogene antibody, DEK antibody, Dek antibody, dek.L antibody, LOC398543 antibody
- 背景
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DEK is a protein with one SAP domain. This protein binds to cruciform and superhelical DNA and induces positive supercoils into closed circular DNA, and is also involved in splice site selection during mRNA processing. Chromosomal aberrations involving this region, increased expression of this gene, and the presence of antibodies against this protein are all associated with various diseases. Two transcript variants encoding different isoforms have been found for this gene.This gene encodes a protein with one SAP domain. This protein binds to cruciform and superhelical DNA and induces positive supercoils into closed circular DNA and is also involved in splice site selection during mRNA processing. Chromosomal aberrations involving this region, increased expression of this gene and the presence of antibodies against this protein are all associated with various diseases. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: D6S231E
Protein Interaction Partner: CUL3, SPOP, UBC, EED, IRF2BP2, GANAB, PTPN12, CSNK2A2, CSNK2A1, TP53BP1, ESR1, VTN, S100A9, RPL37A, DHX15, FTSJ3, WIBG, TMED9, EXOSC2, UTP14A, THRAP3, CAND1, COPS5, CDK2, YWHAZ, Cebpb, ELAVL1, SUMO1, SUMO2, RAD21, HDGF, KAT2B, EP300, CREBBP, HIST1H4A, HDA
Protein Size: 375 - 分子量
- 43 kDa
- 基因ID
- 7913
- NCBI登录号
- NM_003472, NP_003463
- UniProt
- P35659
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