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VEGFR2/CD309 抗体 (N-Term)

Name: VEGFR2/CD309 抗体 (N-Term)
SKU: ABIN2792307
Availability: OutOfStock

VEGFR2 适用: 人, Pig, 犬, Cow, 马 WB, IHC 宿主: 兔 Polyclonal unconjugated

WB Suggested Anti-KDR Antibody Titration: 0. (VEGFR2/CD309 抗体 (N-Term))

Image no. 1 for anti-VEGF Receptor 2 (VEGFR2) (N-Term) antibody (ABIN2792307) (VEGFR2/CD309 抗体 (N-Term))

Researcher: Department of Pathology, Hospital de Carabineros de Chile, Santiago, ChileApplication: IHCSpecies+tissue/cell type: Control-Human Placenta, Sample-Human colorectal cancer Primary Antibody dilution: 1:100Secondary Antibody: Biotinylated pig anti-rabbit+streptavidin-HRP (VEGFR2/CD309 抗体 (N-Term))

IHC

KDR in endothelial cells in blood vessels in placenta was detected using HRP/AEC red color stain. (VEGFR2/CD309 抗体 (N-Term))

IHC

4 images

产品编号 ABIN2792307

发货至: 中国

Datasheet as PDF

抗原 See all VEGFR2/CD309 (VEGFR2) 抗体

VEGFR2/CD309 (VEGFR2) (VEGF Receptor 2 (VEGFR2))
抗原表位
42

36

27

25

20

16

15

15

10

10

8

8

6

6

6

5

5

3

3

3

3

2

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
N-Term
适用
296

183

128

8

4

3

3

2

2

1

1

1

1

1

1

1

1

1

1

1
人, Pig, 犬, Cow, 马
宿主
287

52

15

1

1

1
兔
Compatible Secondaries
克隆类型
280

77
多克隆
标记
161

33

19

13

12

11

7

7

7

7

7

7

5

5

5

5

5

5

5

5

5

5

5

2

2

1

1

1

1

1

1

1
This VEGFR2/CD309 antibody is un-conjugated
应用范围
221

132

95

71

63

24

22

18

13

13

12

11

9

8

7

4

2

2

1
Western Blotting (WB), Immunohistochemistry (IHC)

序列

LNVGIDFNWE YPSSKHQHKK LVNRDLKTQS GSEMKKFLST LTIDGVTRSD

预测反应

Cow: 86%, Dog: 100%, Horse: 100%, Human: 100%, Pig: 100%

产品特性

This is a rabbit polyclonal antibody against KDR. It was validated on Western Blot using a cell lysate as a positive control.

纯化方法

Affinity Purified

免疫原

The immunogen is a synthetic peptide directed towards the N terminal region of human KDR

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anti-VEGF Receptor 2 (VEGFR2) (AA 1326-1356), (C-Term) antibody
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应用备注

Optimal working dilutions should be determined experimentally by the investigator.

说明

Antigen size: 1356 AA

限制

仅限研究用
状态

Liquid

浓度

Lot specific

缓冲液

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freeze-thaw cycles.

储存条件

-20 °C

储存方法

For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
抗原

VEGFR2/CD309 (VEGFR2) (VEGF Receptor 2 (VEGFR2))

别名

KDR (VEGFR2 产品)

别名

CD309 antibody, FLK1 antibody, VEGFR antibody, VEGFR2 antibody, 6130401C07 antibody, Flk-1 antibody, Flk1 antibody, Krd-1 antibody, Ly73 antibody, VEGFR-2 antibody, sVEGFR-2 antibody, Vegfr-2 antibody, FLK-1 antibody, flk-1 antibody, vegfr-2 antibody, KDR antibody, FLK/KDR antibody, flk1 antibody, flk1b antibody, kdrb antibody, si:busm1-205d10.1 antibody, si:ch211-254j6.1 antibody, si:ch211-278f21.4 antibody, wu:fc31a09 antibody, fk52c05 antibody, flk antibody, kdr antibody, kdra antibody, vegfr2 antibody, vegfr4 antibody, vegr2 antibody, wu:fk52c05 antibody, kinase insert domain receptor antibody, kinase insert domain protein receptor antibody, vascular endothelial growth factor receptor kdr-like antibody, kinase insert domain receptor (a type III receptor tyrosine kinase) antibody, kinase insert domain receptor like antibody, KDR antibody, Kdr antibody, LOC100136647 antibody, kdr antibody, kdrl antibody

背景

KDR is the receptor for VEGF or VEGFC. It has a tyrosine-protein kinase activity. The VEGF-kinase ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions.
Alias Symbols: CD309, FLK1, VEGFR, VEGFR2
Protein Interaction Partner: FBXO25, VEGFA, MYO1C, CAV1, NPM1, EPN1, SRC, CBL, IQGAP1, UBC, CSNK1D, FBXW11, BTRC, CUL1, AIMP2, SHC2, SYNGAP1, ACP1, ATR, FRS2, SH2D2A, DNM2, NRP1, VEGFC, GRB10, CDH5, GNAQ, SHC1, STAT1, NCK1, SHB, PLCG2, P2RY2, BMX, FIGF, KDR, TIMP3, PTPN6, PTPN11, ITG
Protein Size: 1356

分子量

151 kDa

基因ID

3791

NCBI登录号

NM_002253, NP_002244

UniProt

P35968

途径

RTK signaling, Glycosaminoglycan Metabolic Process, Signaling Events mediated by VEGFR1 and VEGFR2, Growth Factor Binding, Regulation of long-term Neuronal Synaptic Plasticity, VEGF Signaling