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RAB8A 抗体 (Middle Region)

RAB8A 适用: 人, 小鼠, 大鼠, 犬, Cow, Pig, 绵羊, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2792290
发货至: 中国
  • 抗原 See all RAB8A 抗体
    RAB8A (RAB8A, Member RAS Oncogene Family (RAB8A))
    抗原表位
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    适用
    • 35
    • 11
    • 10
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠, 犬, Cow, Pig, 绵羊, 斑马鱼
    宿主
    • 19
    • 11
    • 4
    克隆类型
    • 24
    • 11
    多克隆
    标记
    • 21
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This RAB8A antibody is un-conjugated
    应用范围
    • 19
    • 9
    • 7
    • 6
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    序列
    GIKFMETSAK ANINVENAFF TLARDIKAKM DKKLEGNSPQ GSNQGVKITP
    预测反应
    Cow: 100%, Dog: 100%, Human: 100%, Mouse: 85%, Pig: 100%, Rat: 85%, Sheep: 100%, Zebrafish: 85%
    产品特性
    This is a rabbit polyclonal antibody against RAB8A. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the middle region of human RAB8A
    Top Product
    Discover our top product RAB8A Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 207 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    RAB8A (RAB8A, Member RAS Oncogene Family (RAB8A))
    别名
    RAB8A (RAB8A 产品)
    别名
    rab8A antibody, DDBDRAFT_0206521 antibody, DDBDRAFT_0214885 antibody, DDB_0206521 antibody, DDB_0214885 antibody, HSH2D antibody, mel antibody, rab8 antibody, c-mel antibody, MEL antibody, RAB8 antibody, zgc:162699 antibody, AA409338 antibody, Mel antibody, Rab8 antibody, rab8A protein antibody, Rab GTPase antibody, RAB8A, member RAS oncogene family antibody, RAB8A, member RAS oncogene family S homeolog antibody, rab8A antibody, RAB8A antibody, rab8a antibody, rab8a.S antibody, Rab8a antibody
    背景
    RAB8A is a member of the RAS superfamily which are small GTP/GDP-binding proteins with an average size of 200 amino acids. The RAS-related proteins of the RAB/YPT family may play a role in the transport of proteins from the endoplasmic reticulum to the Golgi and the plasma membrane. The putative effector-binding site of this protein is similar to that of the RAB/YPT proteins. However, this protein contains a C-terminal CAAX motif that is characteristic of many RAS superfamily members but which is not found in YPT1 and the majority of RAB proteins. Although this gene was isolated as a transforming gene from a melanoma cell line, no linkage between MEL and malignant melanoma has been demonstrable.The protein encoded by this gene is a member of the RAS superfamily which are small GTP/GDP-binding proteins with an average size of 200 amino acids. The RAS-related proteins of the RAB/YPT family may play a role in the transport of proteins from the endoplasmic reticulum to the Golgi and the plasma membrane. This protein shares 97 % , 96 %, and 51 % similarity with the dog RAB8, mouse MEL, and mouse YPT1 proteins, respectively and contains the 4 GTP/GDP-binding sites that are present in all the RAS proteins. The putative effector-binding site of this protein is similar to that of the RAB/YPT proteins. However, this protein contains a C-terminal CAAX motif that is characteristic of many RAS superfamily members but which is not found in YPT1 and the majority of RAB proteins. Although this gene was isolated as a transforming gene from a melanoma cell line, no linkage between MEL and malignant melanoma has been demonstrable. This oncogene is located 800 kb distal to MY09B on chromosome 19p13.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: MEL, RAB8
    Protein Interaction Partner: TFRC, SYTL4, SYTL1, TBC1D17, STAU1, UBC, MDM2, RPA3, RPA2, RPA1, STK4, OPTN, Myo5b, MYO5C, EHD3, EHD1, UBL4A, RAB1B, RAB31, COX5A, RAB11B, RAB7A, SCP2, RRBP1, NDUFA7, IDH3G, SNCA, ELAVL1, Rab8a, RPH3A, RAB3IP, RIMS2, RPH3AL, RABIF, MAP4K2, PDE6D, GDI2, OC
    Protein Size: 207
    分子量
    24 kDa
    基因ID
    4218
    NCBI登录号
    NM_005370, NP_005361
    UniProt
    P61006
    途径
    M Phase, Regulation of long-term Neuronal Synaptic Plasticity, SARS-CoV-2 Protein Interactome
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