CHRNA3 抗体 (N-Term)
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- 抗原 See all CHRNA3 抗体
- CHRNA3 (Cholinergic Receptor, Nicotinic, alpha 3 (Neuronal) (CHRNA3))
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抗原表位
- N-Term
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适用
- 人, 小鼠, 大鼠, Cow, 犬, 兔, 豚鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CHRNA3 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- QEERLLADLM QNYDPNLRPA ERDSDVVNVS LKLTLTNLIS LNEREEALTT
- 预测反应
- Cow: 92%, Dog: 100%, Guinea Pig: 92%, Human: 100%, Mouse: 85%, Rabbit: 100%, Rat: 85%
- 产品特性
- This is a rabbit polyclonal antibody against CHRNA3. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Protein A purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human CHRNG
- Top Product
- Discover our top product CHRNA3 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 505 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- CHRNA3 (Cholinergic Receptor, Nicotinic, alpha 3 (Neuronal) (CHRNA3))
- 别名
- CHRNA3 (CHRNA3 产品)
- 背景
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The mammalian muscle-type acetylcholine receptor is a transmembrane pentameric glycoprotein with two alpha subunits, one beta, one delta, and one epsilon (in adult skeletal muscle) or gamma (in fetal and denervated muscle) subunit. This gene, which encodes the gamma subunit, is expressed prior to the thirty-third week of gestation in humans. The gamma subunit of the acetylcholine receptor plays a role in neuromuscular organogenesis and ligand binding and disruption of gamma subunit expression prevents the correct localization of the receptor in cell membranes. Mutations in this gene cause Escobar syndrome and a lethal form of multiple pterygium syndrome. Muscle-type acetylcholine receptor is the major antigen in the autoimmune disease myasthenia gravis.[
Alias Symbols: ACHRG
Protein Interaction Partner: Ubqln1, CHRNB4,
Protein Size: 517 - 分子量
- 57 kDa
- 基因ID
- 1146
- NCBI登录号
- NM_000743, NP_000734
- UniProt
- Q86U77
- 途径
- Synaptic Membrane
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