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CHRNA7 抗体 (N-Term)

Name: CHRNA7 抗体 (N-Term)
SKU: ABIN2792250
Availability: OutOfStock

CHRNA7 适用: 人, 大鼠, 小鼠, Cow WB 宿主: 兔 Polyclonal unconjugated

WB Suggested Anti-CHRNA7 Antibody Titration: 2. (CHRNA7 抗体 (N-Term))

Host: Rabbit Target Name: CHRNA7 Sample Type: MDA-MB-435S Cell lysates Antibody Dilution: 1. (CHRNA7 抗体 (N-Term))

Host: Rabbit Target Name: CHRNA7 Sample Tissue: Human Jurkat Antibody Dilution: 1. (CHRNA7 抗体 (N-Term))

Host: Rat Target Name: CHRNA7 Sample Tissue: Rat Brain Antibody Dilution: 1ug/ml (CHRNA7 抗体 (N-Term))

4 images

产品编号 ABIN2792250

发货至: 中国

Datasheet as PDF

抗原 See all CHRNA7 抗体

CHRNA7 (Cholinergic Receptor, Nicotinic, alpha 7 (Neuronal) (CHRNA7))
抗原表位
15

14

8

5

3

3

3

2

2

2

2

1

1

1

1

1

1
N-Term
适用
62

35

31

7

5

4

4

3

3

3

2

1
人, 大鼠, 小鼠, Cow
宿主
52

12

2
兔
Compatible Secondaries
克隆类型
52

13
多克隆
标记
28

5

4

3

3

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This CHRNA7 antibody is un-conjugated
应用范围
54

23

13

13

10

6

5

4

3

3

3

2

1

1
Western Blotting (WB)

序列

QGEFQRKLYK ELVKNYNPLE RPVANDSQPL TVYFSLSLLQ IMDVDEKNQV

预测反应

Cow: 93%, Human: 100%, Mouse: 100%, Rat: 100%

产品特性

This is a rabbit polyclonal antibody against CHRNA7. It was validated on Western Blot using a cell lysate as a positive control.

纯化方法

Protein A purified

免疫原

The immunogen is a synthetic peptide directed towards the N terminal region of human CHRNA7

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Discover our top product CHRNA7 Primary Antibody
anti-Cholinergic Receptor, Nicotinic, alpha 7 (Neuronal) (CHRNA7) (AA 52-259) antibody
CHRNA7 适用: 人 WB, ELISA, IHC, ICC, FACS, Neut 宿主: 小鼠 Monoclonal 7F10G1 unconjugated

anti-Cholinergic Receptor, Nicotinic, alpha 7 (Neuronal) (CHRNA7) (AA 441-502) antibody
CHRNA7 适用: 人, 大鼠, 小鼠 WB, ELISA, ICC, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Cholinergic Receptor, Nicotinic, alpha 7 (Neuronal) (CHRNA7) (AA 52-259) antibody
CHRNA7 适用: 人, 大鼠 WB, ELISA, IHC, ICC, FACS, Neut 宿主: 小鼠 Monoclonal 7F10F1 unconjugated

anti-Cholinergic Receptor, Nicotinic, alpha 7 (Neuronal) (CHRNA7) (AA 23-230) antibody
CHRNA7 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated

anti-Cholinergic Receptor, Nicotinic, alpha 7 (Neuronal) (CHRNA7) (AA 23-230) antibody
CHRNA7 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Cholinergic Receptor, Nicotinic, alpha 7 (Neuronal) (CHRNA7) (AA 31-42), (Extracellular), (N-Term) antibody
CHRNA7 适用: 人, 大鼠, 小鼠 WB, IHC, ICC, FACS, IF, LCI 宿主: 兔 Polyclonal unconjugated

anti-Cholinergic Receptor, Nicotinic, alpha 7 (Neuronal) (CHRNA7) (Internal Region) antibody
Verified CHRNA7 适用: 人, 大鼠 ELISA, IHC 宿主: 山羊 Polyclonal unconjugated

anti-Cholinergic Receptor, Nicotinic, alpha 7 (Neuronal) (CHRNA7) (C-Term) antibody
CHRNA7 适用: 人, 大鼠, 小鼠, Cow, 犬, 马, 豚鼠, 兔 WB 宿主: 兔 Polyclonal unconjugated

anti-Cholinergic Receptor, Nicotinic, alpha 7 (Neuronal) (CHRNA7) (AA 22-71) antibody
CHRNA7 适用: 人, 大鼠, 小鼠, 猴, 兔 WB 宿主: 兔 Polyclonal unconjugated

anti-Cholinergic Receptor, Nicotinic, alpha 7 (Neuronal) (CHRNA7) (AA 398-447) antibody
CHRNA7 适用: 人, Cow, 小鸡, 猴, 马, Pig, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated

应用备注

Optimal working dilutions should be determined experimentally by the investigator.

说明

Antigen size: 502 AA

限制

仅限研究用
状态

Liquid

浓度

Lot specific

缓冲液

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freeze-thaw cycles.

储存条件

-20 °C

储存方法

For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
抗原

CHRNA7 (Cholinergic Receptor, Nicotinic, alpha 7 (Neuronal) (CHRNA7))

别名

CHRNA7 (CHRNA7 产品)

别名

CHRNA7-2 antibody, NACHRA7 antibody, dZ70B1.1 antibody, Acra7 antibody, alpha7 antibody, BTX antibody, NARAD antibody, nAChRa7 antibody, CHRNA7 antibody, cholinergic receptor nicotinic alpha 7 subunit antibody, neuronal acetylcholine receptor subunit alpha-7 antibody, cholinergic receptor, nicotinic, alpha 7 (neuronal) antibody, cholinergic receptor, nicotinic, alpha polypeptide 7 antibody, cholinergic receptor, nicotinic, alpha 7 antibody, CHRNA7 antibody, LOC100374356 antibody, chrna7 antibody, Chrna7 antibody, LOC100060521 antibody

背景

The nicotinic acetylcholine receptors (nAChRs) are members of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. The nAChRs are thought to be hetero-pentamers composed of homologous subunits. The proposed structure for each subunit is a conserved N-terminal extracellular domain followed by three conserved transmembrane domains, a variable cytoplasmic loop, a fourth conserved transmembrane domain, and a short C-terminal extracellular region. The protein encoded by this gene forms a homo-oligomeric channel, displays marked permeability to calcium ions and is a major component of brain nicotinic receptors that are blocked by, and highly sensitive to, alpha-bungarotoxin. Once this receptor binds acetylcholine, it undergoes an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. CHRNA7 is located in a region identified as a major susceptibility locus for juvenile myoclonic epilepsy and a chromosomal location involved in the genetic transmission of schizophrenia. An evolutionarily recent partial duplication event in this region results in a hybrid containing sequence from CHRNA7 and a novel FAM7A gene.
Alias Symbols: NACHRA7, CHRNA7-2
Protein Interaction Partner: ATXN1, ADCY6, PIK3R1, APP, FYN,
Protein Size: 502

分子量

56 kDa

基因ID

1139

NCBI登录号

NM_000746, NP_000737

UniProt

P36544

途径

Synaptic Membrane