CCR8 抗体 (Middle Region)
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- 抗原 See all CCR8 抗体
- CCR8 (Chemokine (C-C Motif) Receptor 8 (CCR8))
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抗原表位
- Middle Region
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适用
- 人, Cow, 兔
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CCR8 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- MATIPLLVFY QVASEDGVLQ CYSFYNQQTL KWKIFTNFKM NILGLLIPFT
- 预测反应
- Cow: 93%, Human: 100%, Rabbit: 81%
- 产品特性
- This is a rabbit polyclonal antibody against CCR8. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Protein A purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human CCR8
- Top Product
- Discover our top product CCR8 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 355 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- CCR8 (Chemokine (C-C Motif) Receptor 8 (CCR8))
- 别名
- CCR8 (CCR8 产品)
- 背景
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CCR8 is a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptors are important for the migration of various cell types into the inflammatory sites. This receptor protein preferentially expresses in the thymus. I-309, thymus activation-regulated cytokine (TARC) and macrophage inflammatory protein-1 beta (MIP-1 beta) have been identified as ligands of this receptor. Studies of this receptor and its ligands suggested its role in regulation of monocyte chemotaxis and thymic cell apoptosis. More specifically, this receptor may contribute to the proper positioning of activated T cells within the antigenic challenge sites and specialized areas of lymphoid tissues. Its gene is located at the chemokine receptor gene cluster region.
Alias Symbols: CY6, TER1, CCR-8, CKRL1, CDw198, CMKBR8, GPRCY6, CMKBRL2, CC-CKR-8
Protein Interaction Partner: TPST2, TPST1, CCR8, CCL17, CCL16, CCL4, CCL1,
Protein Size: 355 - 分子量
- 41 kDa
- 基因ID
- 1237
- NCBI登录号
- NM_005201, NP_005192
- UniProt
- P51685
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